Abstract: Objective  To explore the effect of B-ultrasound-guided paravertebral block and general anesthesia on the cognitive function and early recovery quality of elderly patients after thoracoscopic lobectomy.
Methods  A total of 100 elderly patients undergoing thoracoscopic lobectomy were selected and divided into observation group(n=50) and control group(n=50) according to the random number table method. The control group underwent general anesthesia, and the observation group underwent B-ultrasound-guided paravertebral block and general anesthesia. The mini-mental state examination(MMSE) scores, visual analogue scale(VAS) scores for pain at rest and during cough, surgery-related indicators, recovery quality, and occurrence of adverse reactions were compared between two groups.
Results  After anesthesia, the MMSE scores of the two groups were decreased initially and then increased, and the change was slight in the observation group. The difference of interaction between groups, time points and time points between groups was statistically significant(P＜0.05). The VAS scores of the observation group were increased initially and then decreased at rest and during cough. The control group showed a gradually decreasing trend. The VAS scores of the observation group at rest and during cough were lower than those of the control group. The difference of interaction between groups, time points and time points between groups was statistically significant(P＜0.05). The length of ICU stay, extubation time, time to first oral food intake, off-bed time, and length of hospital stay in the observation group were significantly shorter than those in the control group, and the difference was statistically significant(P＜0.05). The scores of pain, self-care ability, psychological and physical comfort, and emotional status of the observation group were significantly higher than those of the control group, and the difference was statistically significant(P＜0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, and the difference was statistically significant(P＜0.05).
Conclusion  B-ultrasound-guided paravertebral block and general anesthesia can effectively improve the cognitive function of elderly patients after thoracoscopic lobectomy and improve their early recovery quality.

Key words: endoscopic lobectomy, paravertebral block, general anesthesia, aged