Abstract: Objective To explore the effect of psychological intervention of ADOPT problem-solving model on alcohol withdrawal, mental flexibility and adaptability in patients with chronic alcoholic liver disease(ALD). 
Methods A total of 142 patients with chronic ALD were selected as the research subjects, and were divided into control group(n=71) and research group(n=71) according to the order of admission. The control group received routine nursing intervention, and on this basis, the research group was supplemented with psychological intervention of the ADOPT problem-solving model. The alcohol dependence［Michigan alcoholism screening test(MAST) scale evaluation］, Barratt impulsivity, self-efficacy［referring to general self efficacy scale(GSES) evaluation］, psychological resilience［connor-Davidson resilience scale(CD-RISC) assessment, including the three dimensions of toughness, optimism, and self-improvement］, and psychosocial adaptability［psychosocial adaptability scale(SPAS) evaluation, including three dimensions of continuous worry, acceptance, and positive attitude towards life］ scores and alcohol compliance and nursing satisfaction before and after intervention of the two groups were compared. 
Results After the intervention, the MAST and Barratt impulsivity scores of the research group were lower than those before intervention, and the above indicators were lower in the research group than in the control group(P＜0.05). The GSES score was higher in both groups, which was higher in the research group than in the control group; there were significant difference in interaction between groups, time points, and time points between groups(P＜0.05). After the intervention, the CD-RISC scores of toughness, optimism, and self-improvement were higher than those before the intervention, which were higher in the research group than in the control group(P＜0.05). After the intervention, the SPAS scores of continuous worry, acceptance, and positive attitude towards life were higher than those before the intervention, which were higher in the research group than in the control group(P＜0.05). The alcohol compliance rate and nursing satisfaction were higher in the research group than in the control group(P＜0.05). 
Conclusion The psychological intervention of the ADOPT problem-solving model can improve the self-efficacy, mental flexibility and adaptability of chronic ALD patients, reduce alcohol dependence and impulsivity, and have a high rate of compliance with alcohol withdrawal and nursing satisfaction. 

Key words: liver diseases, alcoholic, psychotherapy, ADOPT problem-solving model