Abstract: Objective To investigate the application effect of three different packing materials in endoscopic dacryocystorhinostomy. 
Methods Ninety patients(90 eyes) with chronic dacryocystitis were included in the prospective single-blind study and were randomly divided into nasopore group, merocel group and vaseline gauze group, with 30 cases(30 eyes) in each group. All patients underwent endoscopic dacryocystorhinostomy. The patients in the three groups were filled with nasopore, merocel and vaseline gauze to stop bleeding separately. The visual analogue scale(VAS), surgical efficacy and complications were observed. 
Results The VAS of nasopore group was lower than that of merocel group and vaseline gauze group, and effective rate was higher than that of merocel group and vaseline gauze group, suggesting significant difference(P＜0.05). There was no significant difference in the incidence of postoperative complications among three groups(P＞0.05). 
Conclusion Nasopore used in endoscopic dacryocystorhinostomy can reduce postoperative discomfort, accelerate the regeneration of nasal mucosa epithelium, reduce the occurrence of granuloma and adhesion, and improve the success rate of operation. 

Key words: dacryocystitis, dacryocystorhinostomy, packing material