Abstract: Objective To evaluate the feasibility and short- and medium-term clinical efficacy of artificial chordae tendineae in the treatment of posterior leaflet prolapse of the mitral valve.  
Methods A total of 99 patients diagnosed with mitral valve prolapse and regurgitation who underwent mitral valvoplasty at the Second Hospital of Hebei Medical University were selected, including 41 patients with simple anterior leaflet prolapse, 44 patients with simple posterior leaflet prolapse, 4 patients with both anterior and posterior leaflet prolapse, and 10 patients with junctional prolapse.We used artificial chordae tendineae to correct mitral regurgitation in 48 patients with posterior leaflet prolapse. 
Results In total, 48 patients who were given artificial chordae tendineae to correct posterior leaflet regurgitation were followed up for 13-81 months, with an average of (40.60±15.57) months. There was 0 patient who underwent re-operation due to mitral valve disease at 1 year after surgery, 2 patients who underwent re-operation at 2 years after operation, and 2 patients who underwent re-operation at 5 years after surgery, accounting for 4.2% of all patients receiving posterior valvoplasty. Postoperatively, patients showed significant improvements in left ventricular ejection fraction, left ventricular end diastolic diameter, mitral regurgitation area, and cardiac function, as compared with preoperative levels, with statistical differences. Follow-up data showed that these indicators improved more significantly from 6 months to 1 year after surgery. The area of mitral regurgitation gradually increased with time, but currently there was no significant difference. The postoperative mitral valve orifice blood flow velocity, blood flow velocity of left ventricular outflow tract, and mitral valve orifice area were all within the normal range, and no stenosis of mitral valve was found. 
Conclusion Artificial chordae tendineae is effective in the treatment of posterior leaflet prolapse of the mitral valve, which can achieve favorable therapeutic results. 

Key words: heart valve diseases, mitral valvoplasty, mitral valve insufficiency