Journal of Hebei Medical University ›› 2024, Vol. 45 ›› Issue (9): 1002-1006.doi: 10.3969/j.issn.1007-3205.2024.09.003

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Clinical observation on the combination of stellate ganglion block and YS1001P therapeutic instrument in the treatment of acute cerebral infarction with dysphagia

  

  1. 1.Department of Neurology, the Second Affiliated Hospital of Hebei North University, Zhangjiakou 
    075100, China; 2.Department of Function, the Second Affiliated Hospital of Hebei North 
    University, Zhangjiakou 075100, China; 3.Department of Rehabilitation, the Second 
    Affiliated Hospital of Hebei North University, Zhangjiakou 075100, China

  • Online:2024-09-25 Published:2024-09-30

Abstract: Objective To explore the clinical efficacy of stellate ganglion block combined with YS1001P therapeutic instrument in the treatment of acute cerebral infarction (ACI) with dysphagia. 
Methods In total, 80 patients with ACI and dysphagia of the Second Affiliated Hospital of Hebei North University were enrolled in this study, and then divided into two groups according to the random number table method, with 40 patients in each group. Both groups received symptomatic treatment after stroke, including control of blood pressure and blood sugar, anti-platelet aggregation, regulation of lipid metabolism, improvement of cerebral circulation, nutrition of cranial nerves, and prevention and treatment of complications. On this basis, swallowing and neuromuscular electrical stimulator YS1001P was used for treatment. The research group received additional stellate  ganglion block treatment. After 20 d, Kubota Water Swallowing Test was used to evaluate the clinical efficacy of patients. The swallowing function of patients in the two groups before and after treatment was compared with the score of Fujishima Ichiro Dysphagia scale and videofluoroscopic swallowing study (VFSS), and the changes of serum nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) before and after treatment were compared between the control group and the research group. 
Results After treatment, the score of Fujishima Ichiro Dysphagia scale in the research group was higher than that in the control group (P<0.05). After treatment, the scores of oral phase, pharyngeal phase, aspiration, and total VFSS scores in the research group were higher than those in the control group (P<0.05), and the grading of Kubota Water Swallowing Test in the research group was better (P<0.05). The total effective rate of 95.00% in the research group was significantly higher than 77.50% in the control group (P<0.05), and the serum NGF and BDNF levels in the research group were higher than those in the control group (P<0.05). 
Conclusion The combination of stellate ganglion block and YS1001P treatment instrument has a good clinical efficacy in the treatment of ACI with dysphagia. The swallowing function of patients has significantly improved, and its mechanism of action may be related to the improvement of neurotrophic levels. 


Key words: cerebral infarction, difficulty swallowing, stellate ganglion block