Abstract: Objective To explore the application value of concentrated growth factor (CGF) fibrin solution combined with Bio-Oss bone powder in the repair of jawbone defects. 
Methods Eighty patients with jawbone defects after jaw cyst surgery in the 17th Metallurgical Hospital were selected and divided into an observation group (n=40) and a control group (n=40) using a random number table method. The control group was treated with Bio-Oss bone powder, while the observation group was supplemented with CGF fibrin solution on the basis of the control group. The healing of incisions in the two groups was compared, the computed tomography (CT) values of the bone defect filling area were measured, and the bone resorption, bone density, jawbone height and width, and incidence of complications between the two groups were detected. 
Results The observation group showed better wound healing than the control group (P＜0.05). The CT values of the bone defect filling areas in both groups showed a trend of first increasing and then decreasing, reaching a peak at one month after surgery. The CT values of the bone defect filling areas in the observation group were higher than those in the control group, and there were significant differences in the interaction between groups, time points, and time points between groups (P＜0.05). At 6 months after surgery, the bone resorption and bone density of both groups were higher than those at 3 months after surgery, and the height of the maxilla as well as the height and width of the mandible was higher than that at 3 months after surgery (P＜0.05). At 3 months and 6 months after surgery, the bone resorption and bone density of the observation group were lower than those of the control group, while the height of the maxilla as well as the height and width of the mandible was higher than that of the control group (P＜0.05). The total incidence of complications in the observation group was lower than that in the control group (P＜0.05). 
Conclusion The use of CGF fibrin solution combined with Bio-Oss bone powder for the treatment of patients with jawbone defects after after jawcyst surgery can not only promote bone repair, bone healing, and jawbone shape recovery, but also reduce bone resorption, and improve bone density, with good safety. 

Key words: jawcyst, concentrated growth factor, Bio-Oss bone powder