Journal of Hebei Medical University

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Clinical study on the therapeutic scheme and curative effect of retreating postoperative spinal tuberculosis

  

  1. 1.Department of  Orthopedics, the Chest Hospital of Hebei Province, Shijiazhuang 050041, China;
    2.Department of  Emergency, the General Hospital of Hebei Province, Shijiazhuang 050051, China
  • Online:2016-05-25 Published:2016-05-20

Abstract: [
Abstract ] Objective Toinvestigatethetherapeuticschemeandcurativeeffectofretreating
postoperativespinaltuberculosis.Methods Atotalof35patientswithpostoperativerecurrence
ofspinaltuberculosis underwentindividualtreatment , which werestudied retrospectively.
Individualoperation wasperformed : 10cases withdebridementandsinusresection , 5 with
debridementandinterbodyfusion , 8 withdebridement , interbodyfusionandanteriorinernal
fixation , 7withdebridement , interbodyfusionanddislodgmentofinternalfixator , 5withone
stagedebridement , interbodyfusion , dislodgmentofprimaryinternalfixator , combinedanterior
or posterior internal fixation. All patients were followed regularly , and treated by
antituberculosischemotherapyfor18~24months.Clinicaleffect , focusheelingandbonefusion
wereevaluatedatfollow-upperiod.Theoutcomeswereretrospectivelyanalysedbypreoperative
andpostoperativeVisualAnalogueScale ( VAS ) scoresand Oswestry DisabilityIndex ( ODI )
scores.Results Thefollow-upperiod wererangedfrom 28to48 months.Allcases were recovered , andtherehadnorecurrence.Allhadgoodhealingofbonegraftafteroperation.After
admissiontheVASscoreswasdecreasedfrom6. 41±2.56offirstdayafteradmissionto3. 20±
1.48ataweekafteroperation ( P <0.05 ) .ThereweresignificentimprovementsofODIscores
from65. 34±25.48preoperativelyto15. 42±7.56atthefinalfollow-up ( P <0.01 ) .Conclusion
Thecurativeeffectofretreatingpostoperativespinaltuberculosiswasmultifactoriallyeffectedby
manycomplicatedfactors.Theadequatepreoperativeevaluation , individualantituberculosis
chemotherapyandoperationaccordingtoprevioustherapeuticschemecouldimprovethepain.
Thefunctionalongwithqualityoflifewerekeytoimprovingthecurativeeffect.

Key words:  tuberculosis, spinal , drugtherapy , surgicalprocedures, operative