Abstract: ［Abstract］ Objective〖HTSS〗〓To evaluate the predictive effect of the global registry of acute coronary events(GRACE) score on type 1 cardiorenal syndrome(CRS) in patients with nonST segment elevation acute coronary syndrome(nonST ACS).
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and fiftyone cases patients were divided to CRS group 12 cases and nonCRS group according to the incidence of type 1 CRS. The baseline clinical characteristics and the procedure of coronary interventions were recorded and compared. The incidence of major adverse events was followed up. Receiver operaling characleristics(ROC) curve was used to identify predict effect of GRACE score on type 1 CRS in patients with nonST ACS.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓More patients with nonST segment elevation myocardial infarction were in the CRS group, and both GRACE and CRUSADE scores were higher in the CRS group(P＜005). The incidence of sudden death before admission was higher(P＜005) and the level of hematokrit was lower(P＜005) in CRS group compared to the nonCRS group. The peak levels of creatine kinase and troponin I were higher in CRS group than those in the nonCRS group, while the levels of left ventricular ejection fraction and E/e′ were lower(P＜005). The level of diastolic blood pressure in CRS group was lower(P＜0.05). Logistic regression analysis showed that the GRACE and CRUSADE scores were indepandent risk factors of type 1 CRS in patients with ACS during the hospitalization(P＜005). The area under the ROC curve for ratio was 0.906(95% CI  0.853-0.960，P＜0001).  At a cutoff point of 128, the value of GRACE score exhibited 91.7% sensitivity and 80.6% specificity for detecting type 1 CRS in patients with nonST ACS.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The value of GRACE score could predict type 1 cardiorenal syndrome in nonST ACS patients，with high sensitivity and specificity.

Key words: coronary disease, cardiorenal syndrome, forecasting