Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the pathological classification and postoperative outcome in children with refractory epilepsy induced by focal cortical dysplasia(FCD) and analyze the related factors affecting the surgical efficacy.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Eightysix children with refractory epilepsy undergoing surgery were selected. The excision specimens were classified according to the FCD classification criteria in 2011 International League Against Epilepsy(ILAE), and the postoperative outcome was also judged according to the ILAE Engel criteria.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Pathological results of 86 patients: Simplex FCD 37 cases, of which the FCD Ⅰ 19 cases, FCD Ⅱ type 18 cases; Combining FCD(FCD Ⅲ type) in 49 cases. 86 patients with epilepsy in Engel grade I 57 cases, Engel Ⅱ level 16 cases, Engel Ⅲ level 10 cases, Engel level Ⅳ(3 cases). The total effective rate after operation was 66.3%, of which 20.9% was after FCD alone. The combined FCD is 45.3%. Compared with the group with poor prognosis, there were more patients in the group with good prognosis who had combined type FCD, epileptic focus located in temporal lobe, epileptic focus without adjacent functional area, positive cranial MRI, video eeg showing focal discharge and complete removal of epileptic focus(P＜005). The results of Logistic regression analysis showed that the range of eclampsia excision was an independent prognostic factor affecting the efficacy of pediatric refractory epilepsy surgery caused by FCD.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Complete removal of intracranial epileptic foci is a key factor to improve the postoperative efficacy of children with refractory epilepsy caused by FCD.

Key words: epilepsy; , focal cortical dysplasia； child