Abstract: Objective To discuss the clinical efficiency of epidural anesthesia chloroprocaine combined with different doses of fentanyl in patients undergoing anorectal surgery. Methods One hundred and twenty patients undergoing anorectal surgery were randomly divided into three groups,forty patients in each group,group A,B and C respectively received epidural anesthesia with chloroprocaine combined with fentanyl 1,2,3mg/L. The onset time of anesthesia,the disappeared time of pain sensation, the duration of pain sensation block,the duration of motor block,the degree of muscle relaxation,the visual analogue scale( VAS)scores at 5 min after surgery,the operation time,the discharge time and the incidence rate of adverse reactions were observed and recorded in three groups. Results Compared with group A,the onset time of anesthesia and the disappeared time of pain sensation in group B and group C were shorter;compared with group B,the disappeared time of pain sensation of group C was shorter. The duration of sensory block in group B and group C was longer than that of group A( P﹤0 . 05 ). The VAS score at 5 min after surgery was lower in group B and group C,group C compared with group B was lower ( P﹤0 . 05 ). The duration of motor block of group C was longer than that of group A( P﹤0 . 05 ). The operation time in group B was shorter than that in group A and group C( P ﹤0 . 05 ). Compared with group A and group B,the discharge time in group C was later(P ﹤0. 05). The incidence of adverse reactions in group C was more than that of group A( P﹤0 . 05 ). There were no statistical differences in the degree of muscle relaxation among three groups. Conclusion Epidural chloroprocaine combined with different doses of fentanyl(1mg/L,2mg/L,3mg/L)all can be used in daytime anorectal surgery safely and effectively,but the latter two groups provide the longer analgesic time than the first group and 2mg/L fentanyl is the optimum composite dose with less adverse reactions.

Key words: anus disease, anesthesia and analgesia, monitoring intraoperative