Abstract: Objective To explore the effect of early family oriented intervention on the intellectual development of premature infants. Methods One hundred cases of premature infants were chosen in the study,they were divided into observation group and control group according to randomly number table. The observation group was treated with early family oriented intervention,the control group used with conventional methods of child rearing. Differences were observed between the two groups after the intervention of children with mental development and brain MRI findings. Results After the intervention 3,6,12,18 months,adaptability,gross motor,fine motor,language and social development quotient( DQ)means of two groups increased. There were no statistically significant difference in the scores between two groups 3 months after the intervention( P ﹥ 0. 05),and 6,12,18 months after the intervention,the average of DQ in observation group was significantly higher than that of control group (P ﹤ 0. 01). MRI showed normal 40 cases,abnormalities 10 cases in observation group. For the patients in the control group,MRI was normal in 29 cases,abnormal in 21 cases. The normal proportion of observation group with brain MRI manifestations was higher than that of control group( P ﹤ 0. 01). Conclusion The early implementation of family oriented intervention can improve the intelligence development of premature infants.

Key words: infant, premature, intelligence, magnetic resonance imaging