Abstract: Objective To observe the characteristics of familial exudative vitreoretinopathy (FEVR)on fluorescein fundus angiography (FFA),to discuss the FFA diagnostic criteria in patients who suffered from FEVR,and to improve the clinical diagnostic rate of this disease. Methods Thirteen patients(26 eyes)were diagnosed of FEVR by clinical examination in the Second Hospital of Hebei Medical University.After detailed check in anterior segment and fundus,we classified the eyes according to the criteria of Pendergast for familial exudative vitreoretinopathy.Heidelberg fundus angiography imaging system was applied to inspect 13 patients,and then we recorded and analyzed the characteristics.Results In 1 3 patients(2 6 eyes), 1 5 eyes were at stage 1 with uncompleted vascularization of the periphery,especially in the temporal quadrant,very straight retinal vessels,and more branches of peripheral vessels on FFA;seven eyes were at stage 2 with neovascularization and fluorescein leakage on FFA;two eyes were at stage 3 with limited retinal detachement;two eyes with retinal detachement involving macula were classified as stage 4;no total retinal detachement (stage 5)were observed.Conclusion FFA, as a the specific diagnostic measurement of FEVR,plays an important role in the stage classification of FEVR,and FFA can guide the early diagnosis of FEVR and be of great help in choosing the appropriate treatment.

Key words: vitreoretinopathy, proliferative, fluorescein angiography, early diagnosis