Abstract: Abstract］  ObjectiveTo assess the characteristic of transient ischemic attack patients with intraand extracranial largeartery stenosis. MethodsFiftysix cases of transient ischemic attack patients were divided into two groups, twentyfive cases with intra and extracranial largeartery stenosis(group A), and thirtyone cases without intra and extracranial largeartery stenosis(group B). All the participants were examined by clinical assess, Hamilton Anxiety Scale(HAMA), Hamilton Depression Scale(HAMD), Pittsburgh Sleep Quality Index(PSQI), polysomnography(PSG), imaging examination. The data were compared between the two groups. ResultsThere was no statistical difference between the two groups in terms of the incidence rate of sleep disorder，PSQI scores and the incidence rate of obstructive sleep apnea syndrome(P＞0.05). Total sleep time, total nonrapid eye movement(NREM) time and N3/NREM in group A were shorter than that in group B, and sleep efficiency in group A were lower than that in group B, whereas wakening time and sleep time of N2/NREM in group A were longer than that in group B(P＜0.05). But there was no statistical difference between the two groups in terms of total recording time, sleep latency, rapid eye movement(REM) latency, REM time, and N1/NREM(P＞0.05). ConclusionTIA patients with intraand extracranial largeartery stenosis were more prone to shorter total sleep time, longer wakening time, lower sleep efficiency, shorter total NREM time, longer N2/NREM, shorter N3/NREM, and lower sleep quality.

Key words: ischemic attack, transient, carotid stenosis, polysomnography