Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the perioperative condition and risk factors of liver failure in patients with hepatitis B virusassociated liver cancer with or without liver cirrhosis.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Retrospective study was used to collect 160 cases of HBCC patients hospitalized in our hospital, including 90 cases of liver cirrhosis and 70 cases without cirrhosis. The intraoperative and postoperative conditions of the 2 groups were compared, and the risk factors for postoperative liver failure were analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Compared with the control group, the amount of bleeding was more in the study group and the operation time was longer, the difference was statistically significant(P＜005). The blood transfusion rate and the occlusion rate of the hepatic portal in the study group were slightly higher, but the difference was not statistically significant(P＞005). There was no significant difference in the incidence of perioperative pulmonary complications, abdominal infection, biliary fistula and liver failure between the 2 groups(P＞005). Liver failure is a dependent variable, while sex, age, albumin, aspartate aminotransferase, alanine aminotransferase, total bilirubin, prothrombin time activity, ChildPugh classification, operation time, intraoperative bleeding, blood transfusion, liver resection range, tumor diameter, hepatic portal blockage, cirrhosis being independent variables were analyzed by multiple factor Logistic regression analysis. The results showed that age，ChildPugh classification, intraoperative bleeding, blood transfusion, liver resection were found. Risk factors for liver failure in patients with hepatitis B and liver cancer during perioperative period were excluded.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Liver failure is an independent risk factor for liver failure during the perioperative period of liver cirrhosis in patients with hepatitis B, and the risk of perioperative liver failure in patients with liver cancer and liver cirrhosis is higher than that of patients without liver cirrhosis.

Key words: liver cirrhosis, liver neoplasms, liver failure, acute, risk factors