Journal of Hebei Medical University

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Analysis of co-infection in non-HIV immunosuppressed patients with cytomegalovirus pneumonia#br#

  

  1. The Second Department of Respiratory and Critical Care Medicine, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2019-12-25 Published:2019-12-26

Abstract: [Abstract]Objective〖HTSS〗To analyze the co-infection characteristics of non-human immunodeficiency virus(HIV) immunosuppressed patients with cytomegalovirus pneumonia, so as to provide reference for clinical treatment.
  〖WTHZ〗Methods〖HTSS〗A retrospective case analysis study was used. The data of general condition and co-infection characteristic of 68 patients with cytomegalovirus pneumonia were collected.
  〖WTHZ〗Results〖HTSS〗All of 68 patients were non-HIV infected and were treated with corticosteroids or immunosuppressants for underlying diseases including kidney disease, rheumatic disease, and blood system disease. And most of these patients had complications. More than 70% of the 68 patients had co-infections, including bacterial, fungal, or other atypical pathogen. The overall hospital mortality rate was 33.82%. The immunosuppressed patients who suffered from dermatological disease or had co-morbidity, and patients who had G+ pneumonia or bloodstream infections also had a poor prognosis(P<0.05).
  〖WTHZ〗Conclusion〖HTSS〗Among patients with cytomegalovirus pneumonia secondary to non-HIV infection,autoimmune system diseases after corticosteroids or immunosuppressants treatment are the most common primary diagnosis, with poor prognosis. Patients who suffered from dermatological disease, with co-morbidity or G+ pneumonia, and or bloodstream infections had a poorer prognosis.

Key words: cytomegalovirus infections, pneumonia, immunosuppression