Abstract: ［Abstract］〓Objective〖HTSS〗〓To analyze the varied trend of human immunodeficiency virus(HIV) infection rate among different blood donors from 2011 to 2017, provide data basis for targeted donating blood publicity and establish blood donors recruitment policy.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The blood samples of Hebei Blood Center from 2011 to 2017 were collected, which were reactive by enzymelinked immunosorbent assay(ELISA) of antigen and antibody and HIV positive by immunoblotting confirmatory test; the blood samples which were nonreactive by ELISA detection but HIVRNA reactive by nucleic acid test were also collected. These blood samples showed HIVpositive by retroactive confirmation. The gender, age and occupations distribution characteristics of HIVpositive blood donors were observed. The varied trend of HIV infection rate of different gender, age and occupations voluntary blood donors were analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓1 178 295 blood samples were detected from 2011 to 2017, 149 blood samples were HIVpositive by immunoblotting confirmatory test, 2 blood samples were HIVpositive by nucleic acid test and retroactive confirmation. The rate of HIV infection of blood donors showed a increasing trend(P＜005). HIVpositive blood donors were mainly males(96.03%), the rate of HIV infection of male blood donors were increasing gradually(P＜005). The HIVpositive blood donors were mainly 18-25(33.11%) and 26-35(28.48%) years old. The rate of HIV infection of 18-25 years old blood donors showed increasing trend(P＜005), there was no significant change in the HIV infection rate of the 26-35 years old blood donors(P＞005). HIVpositive blood donors were mainly freelance workers(33.11%) and staffs(25.83%). The rate of HIV infection of staffs showed the trend of gradual increase(P＜005), but there was no significant change in the rate of HIV infection of freelance workers(P＞005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓There are gender, age and occupations distribution characteristics for the HIV infection rate of blood donors in Shijiazhuang. Moreover, the HIV infection rate of the main blood donors show the trend of gradual increase. Blood banks should strengthen the publicity and education of HIV prevention and control knowledge for blood donors, reduce the HIV infection rate and improve blood safety.

Key words: HIV, blood donors, enzymelinked immunosorbent assay