Abstract: Objective To evaluate the short-term therapeutic effect of pedicle screw internal fixation plus inter-lamina bone grafting with calcium phosphate artificial bone and cancellous bone (CPC).Methods Twenty-six patients with thoracolumbar burst fracture were treated in our hospital.The changes of Cobb angle,loss of correction and postoperative back pain were observed 1 week,3 months,6 months,12 months,15 months after operation.Results All patients were followed up.At five different periods of follow-up,vertebral Cobb angle and anterior vertebral height significantly improved,and the back pain significantly eased(P <0.01).However,when the internal fixation had been removed at 15 months after operation,the vertebral collapse happened again in some patients,accompanied by varying degrees of kyphosis which caused back pain. Conclusion Pedicle screw internal fixation plus inter-lamina bone grafting with calcium phosphate artificial bone and CPC improved the stability of fractured verterbra,restored the height of verterbra.However,vertebral collapse in some patients occurred again after internal fixation were removed,leading to the possibility of delayed thoracic back pain and other long-term complications.A variety of bone grafting methods should be considered to treat thoracolumbar burst fractures.

Key words: spinal fracture, fracture fixation, Cobb angle