Abstract: Objective To investigate the value of cardiac troponin I (CTnI)in children of severe pneumonia with myocardial damage.Methods A total of 200 children with severe pneumonia in our hospital were collected as observation group,180 children with mild pneumonia in our hospital in the same period were collected as mild group,200 cases of healthy children in the same period were collected as control group,CTnI level,creatine kinase MB(CK-MB)level of three groups were analyzed and compared.Results The cTnI,CK-MB,creatine Kinase (CK), lactate dehydrogenase(LDH)and aspartate amino-transferase,AST(AST)levels of observation group were significantly higher than those of mild group (P<0.05),and cTnI positive rate of observation group was significantly higher than that of mild group (P<0.05).The difference of CK-MB level between the two groups was not significant(P>0.05).Conclusion Most children of severe pneumonia are associated with varying degrees of myocardial damage,cTnI can be used to monitor the condition of the children as an important marker of myocardial inj ury.Early detection of cTnI is favorable to the early diagnosis and treatment of severe pneumonia with myocardial damage,thereby preventing the occurrence of cardiac failure in the children.

Key words: pneumonia, troponin I, creatine kinase, children