Abstract: OcjectiVe To investigate the clinical pathological factors influencing the accuracy of the diagnosis of tumors by dilatation and curettage. Methods Clinicopathological data of 128 patients with endometrial carcinoma were collected to analyze the pathological diagnostic concordance rate between postoperative permanent section and preoperative dilatation and curettage. The accuracies of the endometrioid adenocarcinoma grades of 98 cases were also compared between the preoperative dilatation and curettage and postoperative pathological findings. Results The preoperative dilatation and curettage in 128 patients with endometrial cancer diagnosis and postoperative permanent section results were related (χ2 = 424 . 958 ,p =0 . 000 ),and the consistency of two results was good( Kappa value 0 . 871 ). The preoperative dilatation and curettage in 98 cases of endometrioid adenocarcinoma classification and postoperative biopsy results were related(χ2 =52 . 648 ,p=0 . 000 ),but the consistency of two results was poor( Kappa value 0 . 348 ). Conclusion The dilation and curettage had some clinical significance in diagnosing pathological analysis of endometrial carcinoma,but it had certain limitations. There was a relatively poor correlation in the diagnosis of endometrial carcinoma between preoperative grade on dilation and curettage and final pathologic analysis. Therefore,the information of tumor grade obtained from the dilation and curettage should be cautiously balanced to prevent its over-treatment or under-treatment.

Key words: endometrial neoplasms, diagnostic techniques, obstetrical and gynecological, pathology