Abstract: ［Abstract］ Objective〖HTSS〗〓To explore and analyze the risk factors associated with maxillofacial multiple space infections.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 115 patients diagnosed with oral and maxillofacial multiple space infection in our hospital were selected as the research subjects, and the clinical data of those patients was retrospectively analyzed. The etiological factors, clinical presentations, laboratory tests and complications were recorded. At the same time, single factor test and Logistic regression analysis were performed to evaluate the factors that caused the prolongation of hospitalization and complications.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Incidence and etiological classification: odontogenic 41/115(35.65%), lymphadenitis 27/115(23.47%), sialadenitis 16/115(13.91%), cyst 16/115(13.91%), trauma and unknown reason 15/115(13.04%), of which odontogenic infection is the most common cause. The number of spaces involved, the number of leukocytes, the blood glucose concentration, the percentage of neutrophils of patients hospitalized≥ 15 days were different of  those of patients hospitalized＜15 days, and the differences were statistically significant(P＜005). The age, associated underlying systemic diseases, the number of spaces involved, the white blood cell count, the blood glucose concentration, percentage of granulocytes  in patients with oral and maxillofacial multiple space infection combined with complications were different of those in patients without complications, and the differences were statistically significant(P＜005). Logistic regression analysis showed that the hospitalization time in patients with oral and maxillofacial multiple space infection was related to the number of spaces involved, white blood cell count, blood glucose concentration and neutrophil percentage. The complications of patients with oral and maxillofacial multiple space infections were related to the number of spaces involved, white blood cell counts, blood glucose levels, neutrophil percentage, and age.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Risk factors associated with hospitalization time and complications in oral and maxillo facial multiple space infections patients included associated underlying systemic diseases, the number of spaces involved, white blood cell count, blood glucose concentration, neutrophil percentage, and age, all the risk factors above were closely related to the prognosis of the disease, Those patients are at higher risk of developing lifethreatening complications and require early adequate treatment of their conditions and close clinical monitoring.

Key words: mouth diseases, maxillofacial multiple space infections, risk factors