Abstract: Objective  To explore the change rules of bone mineral density in patients with benign paroxysmal positional vertigo(BPPV) and the effect of bone mineral density on BPPV.
  Methods  The 105 BPPV patients were selected as the experimental group, and 108 healthy subjects were selected as the control group. Both group are taken ENT specialist examination, nystagmus inspection, position test, and whole body bone density determination(dual energy X-ray absorption method, calculated by T-score). Then we concluded the change rules of the whole body bone mineral density T-value of BPPV patients in different genders and ages, and the effect of bone density on BPPV.
  Results  The T-value of bone mineral density in the experimental group was lower than that in the control group, and the difference was statistically significant(P＜0.05).The bone mineral density T value of the male and female test groups was lower than that of the control group, and the incidence of bone density reduction was higher than that of the control group.The bone mineral density T-value of the two groups of women was lower than that of men, and the incidence of bone density reduction in women was higher than that of men, the difference was statistically significant(P＜0.01).The bone mineral density T-value of the test group between 41 to 50 years old, 51 to 60 years old, 61 to 70 years old, and 71 years or older was lower than that of the control group, and the incidence of bone density reduction was higher than that of the control group. The difference was statistically significant(P＜0.05 or P＜0.01). There was no statistically significant difference in bone mineral density T-value and the incidence of bone mineral density reduction between the test group and the control group younger than or equal to 40 years old(P＞0.05). With the increase of age, the bone density T value of the two groups showed a decreasing trend, and the incidence of bone density decrease showed an increasing trend, and the difference was statistically significant(P＜0.05). Logistic regression analysis showed that bone density reduction was a risk factor for BPPV.
  Conclusion  The T-value of bone mineral density in BPPV patients is significantly lower than that in the normal control group, and showes an increasing trend with age, especially in women. Decreased bone density is a risk factor for BPPV.

Key words: vertigo, bone density, risk factors