Abstract: ［Abstract］ Objective〖HTSS〗To investigate the effect of minimally invasive McKeown operation and excision of esophageal cancer by open transposition of right chest with three incisions in the treatment of esophageal cancer and its influence on Visual Analogue Scale (VAS) and QLICP-ES scores.
  〖WTHZ〗Methods〖HTSS〗Ninety cases of upper and middle esophageal cancer were randomly selected. They were divided into observation group and control group according to random number table method, 45 cases in each group. The control group underwent excision of esophageal cancer by open transposition of right chest with three incisions, while the observation group underwent minimally invasive right enteroventromedial-cervical incision(McKeown) operation. The surgical indicators, complications, pain scores and quality of life of the two groups were observed.
  〖WTHZ〗Results〖HTSS〗The operation time, intraoperative bleeding volume, number of lymph nodes cleared, 24 hour drainage, drainage time and hospitalization time of the observation group were better than those of the control group(P＜0.05). With the extension of the postoperative time, the patient′s pain score gradually decreased, which is more meaningful than the difference of 6 h after surgery, the VAS scores of 6 h, 24 h, 36 h and 72 h were significantly lower than those of the control group, the difference between the establishment comparison, the time point comparison, and the establishment and the time point comparison are all of statistical significance(P＜0.05). Complications such as pneumonia, atelectasis and pleural effusion in the observation group were significantly less than those in the control group, but gastric emptying disorders were significantly higher than those in the control group(P＜0.05). The QLICP-ES scores in the observation group were significantly higher than those in the control group at 3 months and 6 months after operation (P＜0.05). Follow-up for 6 months showed that there were no missing patients, no recurrence in the observation group and 1 recurrence in the control group.
  〖WTHZ〗Conclusion〖HTSS〗Minimally invasive McKeown operation has a good effect on esophagus, with short operation time, less bleeding, more lymph node dissection, fewer complications, less pain and higher quality of life. It can be widely used in clinic.

Key words: esophageal neoplasms, minimally invasive McKeown surgery, traditional thoracotomy