Journal of Hebei Medical University ›› 2021, Vol. 42 ›› Issue (6): 676-679,685.doi: 10.3969/j.issn.1007-3205.2021.06.012

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Analysis on effect of laparoscopic bariatric and metabolic surgery on metabolic syndrome

  

  1. 1.Department of Metabolic and Bariatric Surgery, the Second Hospital of Hebei Medical University, 
    Shijiazhuang 050000, China； 2.Department of Critical Care Medicine, Huanghe Sanmenxia Hospital 
    Affiliated  to Henan University of Science and Technology, Sanmenxia 472000, China； 
    3.Department of Neurology， Sanmenxia Central Hospital Affiliated  to Henan 
    University of Science and Technology, Sanmenxia 472000, China
  • Online:2021-06-25 Published:2021-07-05

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Abstract: Objective  To explore the efficacy of laparoscopic bariatric and metabolic surgery for patients with metabolic syndrome and itseffect. 
Methods  The clinical data of 100 patients with metabolic syndrome who underwent laparoscopic bariatric and metabolic surgery were retrospectively analyzed. Body weight, body mass index(BMI), percentage of excess body weight, triglyceride(TC), high density lipoprotein(HDL), fasting plasma glucose(FPG), glycosylated hemoglobin(HbA1c), homeostasis model assessment insulin resistance index(HOMA-IR), Epworth sleepiness scale(ESS), lowest arterial O2 saturation(LSaO2), as well as improvement of type 2 diabetes mellitus(T2DM), hypertension, fatty liver and knee joint degeneration were recorded before and at 1 year after surgery. 
Results  The surgery was successfully completed for all 100 patients. The body weight, BMI, TC, FPG, HbA1c, HOMA-IR, and ESS scores of patient were gradually decreased after operation. The body weight and BMI at 3, 6 and 12 months after operation were significantly lower than those before operation. The TC at 6 and 12 months after operation was significantly lower than that before operation. FPG, HbA1c and HOMA-IR at 1, 3, 6 and 12 months after operation were significantly lower than those before operation. The ESS scores at 3, 6 and 12 months after operation were significantly lower than those before operation, and the difference was statistically significant(P＜0.05). HDL and LSaO2 of patient were increased gradually after operation; HDL at 6 and 12 months after operation was significantly higher than that before operation, and LSaO2 at 3, 6 and 12 months after operation was significantly higher than that before operation, suggesting significant differences(P＜0.05). At 12 months after operation, the incidence of T2DM, hypertension, fatty liver and degenerative change of joint were significantly lower than that before operation, and the difference was statistically significant(P＜0.05). 
Conclusion  Laparoscopic bariatric and metabolic surgery are safe, reliable and effective in the treatment of obesity-associated metabolic syndrome.


Key words: metabolic syndrome, metabolic and bariatric surgery, obesity