Abstract: ［Abstract］  Objective〖HTSS〗〓To explore the related factors of metabolic syndrome associated nephropathy.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Eightysix obese patients （1 lost） for routine renal function detection in our hospital from March 2010 to March 2014 were selected, who were divided into two groups, 31 patients with normal renal function as group A, and 54 patients with renal injury as group B according to the testing results. All selected patients were treated, and the group B was divided into group B1(renal function were significantly improved,31 cases) and group B2(renal function did not improved,23 cases) according to the result of 12 weeks treatment. The lipids, blood rheology,renal function, blood pressure and glucose of the two groups were detected first came to medical examination and after 12 weeks treatment.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The total cholesterol(TC), triglyceride(TG), fasting blood glucose(FBG), 2hour postprandial glucose(2 hPBG), fasting insulin(FINS), and homeostasis model assessmentinsulin resistance index(HOMAIR) of group B were higher than that of the group A, high density lipoprotein cholesterol(HDLC) was significantly lower that that in group A, the difference was statistically significant(P＜005). The difference of low density lipoprotein cholesterol(LDLC) levels in 2 groups were not statistically significant(P＞005). 24hour urinary protein excretion(24 hUP), blood urea nitrogen(BUN) and mean arterial pressure(MAP) level were significantly higher than that in group A, eGFR level was significantly lower than that in group A(P＜005). The TC, TG, 24 hUP, BUN, FBG, HOMAIR and MAP of group B1 were lower than that in group A, the eGFR of group B1 was significantly higher than that in group B2, the difference was statistically significant(P＜005). Before treatment the blood rheology index of both A, B groups had no significant difference(P＞005); after the treatment the blood rheology index of both A, B groups were significantly lower than that before treatment, blood rheology index of B group were significantly lower than that in group A, the difference was statistically significant(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓HOMAIR and MAP were important cause of the rise of metabolic syndrome associated nephropathy, and can be pointed out for the prevention and treatment of disease.

Key words: metabolic syndrome, acute kidney injury, blood glucose