Abstract: Objective To explore the effect of transcranial direct current stimulation combined with mirror neuron therapy on motor aphasia after ischemic stroke. 
Methods Eighty patients with motor aphasia after ischemic stroke admitted to the hospital were selected and divided into control group(n=40) and experimental group(n=40) according to random number table. Both groups were given basic treatment, the control group was given mirror neuron therapy, and the experimental group was treated with transcranial direct current stimulation on the basis of the control group. Both groups were treated for 20 d. Before and after treatment, the two groups were assessed using the Boston Diagnostic Aphasia Examination(BDAE), Western Aphasia Battery(WAB) and the National Institutes of Health Stroke Scale(NIHSS), and the clinical efficacy, and incidence of adverse reactions were compared between two groups. 
Results After treatment, the difference in BDAE grade distribution between two groups was statistically significant(P＜0.05). After treatment, there was significant difference in the distribution of curative effects between two groups(P＜0.05), and the total effective rate of the experimental group was higher than that of the control group(P＜0.05). After treatment, the WAB scores of both groups were increased(P＜0.05), which were higher in experimental group(P＜0.05), and the NIHSS scores of two groups were decreased(P＜0.05), and which were lower in experimental group(P＜0.05). There was no significant difference in the incidence of adverse reactions between two groups(P＞0.05). 
Conclusion Transcranial direct current stimulation combined with mirror neuron therapy can improve the language function of patients with motor aphasia after ischemic stroke, with a definite effect, good safe and reliability.

Key words: stoke, aphasia, Broca, electric stimulation