河北医科大学学报

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超脉冲CO2激光联合调Q开关532 nm激光治疗脂溢性角化病的疗效观察

  

  1. 河北医科大学第二医院整形外科,河北 石家庄 050000
  • 出版日期:2016-04-25 发布日期:2016-05-18
  • 作者简介:韩兰芹(1965-), 女,河北定州人,河北医科大学第二医院主管护师,医学学士,从事激光治疗皮肤色素性疾病和激光美容研究。

The therapeutic effect observation of the ultrapulsed CO2 laser in combination with Q-switch 532 nm laser on the treatment of the seborrheic keratosis

  1. Department of Plastic surgery, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2016-04-25 Published:2016-05-18

摘要: [摘要] 目的 观察超脉冲 CO 2 激光联合调 Q 开关 532nm 激光治疗脂溢性角化病的疗效及安全性。方法
将 375 例脂溢性角化病门诊患者分成 3 组各 125 例。治疗组采用超脉冲 CO 2 激光联合调 Q 开关 532nm 激光治
疗,对照 1 组单纯采用超脉冲 CO 2 激光治疗,对照 2 组单纯应用多功能电离子治疗仪治疗。结果 治疗组一次性痊
愈率 96.8% ,高于对照 1 组的 83.
2% 和对照 2 组的 78.4% ,差异有统计学意义( P <0.05 )。治疗组总的不良反应
发生率低于对照 2 组( P <0.05 );浅表瘢痕发生率为 0.0% ,明显低于对照 2 组的 7.2% 和对照 1 组的 4.8% ,差异
有统计学意义( P <0.05 );
3 组暂时性色素沉着发生率差异有统计学意义( P <0.05 ),但两两比较差异无统计学意
义( P >0.05 );
3 组色素减退发生率差异无统计学意义( P >0.05 )。结论 超脉冲 CO 2 激光联合调 Q 开关 532nm
激光是治疗脂溢性角化病安全有效的方法,不良反应发生率明显降低。

关键词: 角化病, 脂溢性, 激光疗法, 治疗结果

Abstract: [
Abstract ] Objective Toevaluatethetherapeuticeffectandthesafetyofultra-pulsedCO 2
laserincombinationwiththeQ-switch532nmlaseronthetreatmentoftheseborrheickeratosis.
Methods Threehundredandseventy-fivecasesofoutpatientsdiagnosedasseborrheickeratosis
weredividedintothreegroupsequally , with125casesineachgroup.Treatmentgroupwastreated
withtheultra-pulseCO 2 laserandQ-switch532nmlaser.Controlgroup1wastreatedwiththe
ultra-pulseCO 2 .Controlgroup 2 wastreated with the multifunctionalelectricion therapy
apparatus.Results Theone-timecurerateintreatmentgroupwas96.8% , higherthanthatof
83.2%incontrolgroup1and78.4%incontrolgroup2 , thedifferencewasstatisticallysignificant
(
P <0.05 ) .Generalcomplicationswerelowerintreatmentgroupthanthatcontrolgroup2 ( P <
0.05 ) .Thenumberoftotalcasesofcomplicationsintreatmentgroup waslessthancontrol
group.Andsuperficialscarincidencewas0.0% intreatmentgroup , which wassignificantly
lowerthanthatof7. 2%incontrolgroup2 , orthatof4.8%incontrolgroup1.Thedifference
wasstatisticallysignificant ( P <0.05 ) .Theincidenceoftemporarypigmentationwasstatistically
significantdifferenceamong3groups ( P <0.05 ), butthedifferencebetweentwogroupswasnot
statisticallysignificant ( P >0.05 ) .Theincidenceofpigmentlossrateamong3groupswasnot
statisticallysignificantdifference ( P >0.05 ) .Conclusion UltrapulseCO 2 lasercombinedwiththe
Q-switch532nmlaserintreatmentofseborrheickeratosisisasafeandeffectivemethod , which showsasignificantreducedincidencerateofsideeffects.

Key words: keratosis, seborrheic , lasertherapy , treatmentoutcome