关键词: 输血, 不良反应, 治疗结果

Abstract: ［Abstract］Objective〖HTSS〗To explore the adverse reactions, transfusion efficacy and outcome difference of two kinds of transfusion methods.
〖WTHZ〗Methods〖HTSS〗Seventy patients with autogenous blood transfusion with lumbar fracture(experimental group) and 70 patients with allogeneic blood transfusion with lumbar fracture(control group) were selected. Blood routine examination and coagulation function were carried out before and 1,3,7 days after blood transfusion in both groups. Adverse reactions of blood transfusion were recorded in both groups. The immunoglobulin level, complement level and outcome between two groups was compared.
〖WTHZ〗Results〖HTSS〗The activated partial thromboplastin time and prothrombin time of the two groups showed a trend of first prolonging and then shortening, the difference between time points was statistically significant(P＜0.01), and there was no significant difference between groups and between groups in interaction between time points(P＞0.05). The hematocrit of the two groups first decreased and then increased, the difference between time points was statistically significant(P＜0.01), and there was no significant difference between groups, between groups and time points interaction(P＞0.05). The hemoglobin, platelets and leukocytes of the two groups all decreased first and then increased. The interaction between time points and between groups was statistically significant(P＜0.01), but there was no significant difference between groups(P＞0.05). The blood transfusion of the two groups decreased first and then increased, the change range of the experimental group was large, and the interaction among groups, time points and between groups was statistically significant(P＜0.01). The level of immunoglobulin G and immunoglobulin M decreased in the control group, but not in the experimental group. The level of immunoglobulin G and immunoglobulin M in the experimental group was significantly higher than that in the control group, and the interaction among groups, time points and time points was statistically significant(P＜0.01). There was no significant difference in the interaction of C3 between groups, time points and between groups(P＞0.05). The clinical effect of the experimental group was better than that of the control group, and the incidence of adverse reactions and hospitalization expenses were significantly lower than that of the control group(P＜0.05). There was no significant difference in mortality between two groups(P＞0.05).
〖WTHZ〗Conclusion〖HTSS〗Autotransfusion is superior to allogeneic transfusion in blood transfusion effect and recovery speed. Autotransfusion has the advantages of safety, economy, high cure rate, low incidence of adverse reactions and low mortality.

Key words: blood transfusion, adverse reaction, treatment outcome