河北医科大学学报

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应用成人10年患ASCVD风险评估方法对他汀治疗获益人群的横断面研究

  

  1. 1.北京交通大学社区卫生服务中心,北京 100044;2.北京大学第三医院心内科,卫生部心血管分子生物学与调节肽重点实验室,分子心血管学教育部重点实验室,北京 100191
  • 出版日期:2018-02-25 发布日期:2018-02-06
  • 作者简介:聂颖(1977-),女,四川江油人,北京交通大学社区卫生服务中心副主任医师,医学博士,从事心血管疾病诊治研究。
  • 基金资助:
    北京交通大学科研立项(016JB00040)

A crosssection study of benefiting people with statin therapy by application of 10year ASCVD risk assessment method for adults#br#

  1. 1.Beijing Jiaotong University Community Health Center, Beijing 100044, China; 2.Department of
    Cardiology, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular
    Biology and Regulatory peptide, Ministry of Health, Key Laboratory of Molecular
    Cardiovascular Sciences, Ministry of Education, Beijing 100191, China
  • Online:2018-02-25 Published:2018-02-06

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗应用成人10年患动脉粥样硬化心血管疾病(atherosclerotic cardiovascular disease,ASCVD)风险评估方法对社区居民进行横断面研究,进而探索4种他汀治疗获益人群的具体情况。
〖HTH〗方法〖HTSS〗〖KG*2〗应用2013年美国心脏病学会/美国心脏协会(ACC/AHA)推荐的风险评估方法,对3 516例资料完整的参检者进行分析,按照研究需要计算其中1 891例参检者的10年患ASCVD的风险,进而了解本社区4种他汀治疗获益人群的分布情况及10年患ASCVD风险≥7.5%人群的整体情况。
〖HTH〗结果〖HTSS〗〖KG*2〗本社区4种他汀治疗获益人群751例、10年患ASCVD风险≥7.5%者418例,分别占总入选人数的21.36%和11.89%。10年患ASCVD风险≥7.5%者中,60~69岁者所占比例最高,达49.1%。男性ASCVD评分显著高于女性,差异有统计学意义(P<0.05)。
〖HTH〗结论〖HTSS〗〖KG*2〗社区成人能够从他汀治疗中获益及10年患ASCVD风险≥7.5%者比例较高,且男性风险评分高于女性。

关键词: 动脉粥样硬化, 高血压, 横断面研究

Abstract: [Abstract] Objective〖HTSS〗〓To carry out a crosssection study in community resident by application the 10year atherosclerotic cardiovascular disease(ASCVD)risk assessment method and then to explore the situation of 4 statin benefit groups.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓
Application of the risk assessment mothod was recommended by ACC/AHA in 2013. A total of 3 516 individuals with integrated data were studied. 1 891 individuals were calculated for the 10year ASCVD risk. Then the distribution of 4 statin benefit groups and the situation of an estimated 10year ASCVD risk of 7.5% or higher were respectively found.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Seven hundred and fiftyone patients were benefited from four statin treatments in the community. There were 418 cases with 10 years the risk of ASCVD more than 7.5%.  These people accounted for 21.36% and 11.89% of the total number of candidates. In these 10 years the risk of ASCVD≥ 7.5%, 60-69 years of age accounted for the highest proportion of 49.1%. The score of ASCVD in males was statistically higher than that in females(P<005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The prevalence of statin benefit community individuals and 10year atherosclerotic ASCVD risk of 7.5% or higher in adult were very high. The score of risk estimation in male was more serious than in female.

Key words: atherosclerosis, hypertension, crosssectional studies