关键词: 休克, 出血性, 补液疗法, 免疫, 电解质

Abstract: ［Abstract］〓Objective〖HTSS〗〓To analyze the rescue effect of different fluid resuscitation on traumatic hemorrhagic shock and its influence on immune function and electrolyte level.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and twenty patients with traumatic hemorrhagic shock were randomly divided into limited group(40 cases treated with limited fluid resuscitation), hypertonic saline group(40 cases treated with hypertonic saline resuscitation) and conventional group(40 cases treated with conventional fluid resuscitation). The rescue effect(mortality within 24 h and mortality within 7 d), electrolyte level(concentration of K+, Na+, Cl-, Mg2+), coagulation function(prothrombin time, activation time of partial thromboplastin), complication rate and average infusion volume were compared among the three groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no significant difference in 7day mortality and complication rates between the restricted group and the hypertonic saline group(P＜005). Prothrombin time and activated partial thromboplastin time in the restricted group and the hypertonic saline group were shorter than those in the conventional group, and the infusion volume was less than that in the conventional group(P＜005). There was no significant difference in electrolyte levels between the three groups before and after resuscitation(P＞005). After resuscitation, the levels of K+ and Mg2+ in the three groups were lower than those before resuscitation, and the Na+ levels in the restricted group and the hypertonic saline group were higher than those before resuscitation, with a statistically significant difference(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Limiting group and hyperosmotic salt group can actively improve coagulation function and reduce the incidence of complications compared with the conventional group in the treatment of traumatic hemorrhagic shock.

Key words: shock, hemorrhagic, fluid therapy, immunity, electrolytes