关键词: 结核, 脊柱, 切口不愈合, 危险因素

Abstract: ［Abstract］〓Objective〖HTSS〗〓To identify the risk factors of postoperative wound nonunion in patients with spinal tuberculosis and to reduce the incidence rate.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 146 patients with spinal tuberculosis who underwent surgery were enrolled in this study. The patients basic information and perioperative information were recorded. Multivariate logistic regression analysis was used to analyze the risk factors of wound nonunion after spinal tuberculosis operation. 
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Among 146 cases of spinal tuberculosis, 122 cases(83.56%) had incision healing and 24 cases(16.44%) had incision nonunion. The age of nonhealing group was significantly older than that of healing group, the proportion of extraspinal tuberculosis was higher than that of nonhealing group, the proportion of combined posterior and anterior surgery was higher than that of healing group, the proportion of incomplete removal of surgical lesions was higher than that of healing group, and the level of procalcitonin（PCT） was higher than that of healing group, which showed statistical differences（P＜005）. Multivariate logistic regression analysis showed that age, surgical method, extent of lesion clearance and PCT level were risk factors for incision nonunion after spinal tuberculosis surgery(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Age, combined anterior and posterior surgery, incomplete removal of surgical lesions, and high PCT are risk factors for nonunion of incision after spinal tuberculosis surgery. Reasonable selection of surgical indications is the key to reduce the incidence of incision nonunion after operation.

Key words: tuberculosis, spinal； wound nonunion, risk factors