河北医科大学学报 ›› 2022, Vol. 43 ›› Issue (2): 193-197.doi: 10.3969/j.issn.1007-3205.2022.02.014

• • 上一篇    下一篇

超微血流成像技术评价颈内动脉闭塞的价值及斑块内新血管生成的危险因素分析

  

  1. 河北北方学院附属第一医院超声医学科，河北 张家口 075000
  • 出版日期:2022-02-25 发布日期:2022-03-03
  • 作者简介:马力丰（1982-），男，河北邢台人，河北北方学院附属第一医院主治医师，医学学士，从事超声医学诊断研究。
  • 基金资助:
    河北省医学科学研究重点课题计划（20180870）

Evaluation value of superb micro-vascular imaging for internal carotid artery occlusion and analysis of risk factors for plaque neovascularization plaque formation of new blood vessels

  1. Department of Ultrasound Medicine, the First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China
  • Online:2022-02-25 Published:2022-03-03

HTML

PDF (PC)

59

摘要： 目的 探究超微血流成像技术（superb micro-vascular imaging,SMI）对颈内动脉闭塞的评估价值并分析斑块内新生血管生成的危险因素。
方法 选取在我院超声医学科就诊发现颈动脉均质等回声或低回声斑块的120例肥胖型中青年糖尿病患者，采用SMI及数字减影血管造影（digital subtraction angiography，DSA）检测颈内动脉闭塞情况；据SMI检测结果将患者分为有新生血管组（n=98）及无新生血管组（n=22），统计2组患者临床资料并进行单因素分析，对影响斑块内新生血管生成的相关危险因素进行多因素非条件Logistic回归分析。
结果 SMI与DSA检测120例患者中颈内动脉闭塞概率分别为13.33%与18.33%，两者检测结果一致性较好（Kappa=0.814，P=0.023）。有吸烟史、有冠心病史、有脑梗死病史及血清低密度脂蛋白胆固醇（low-density lipoprotein cholesterol，LDL-C）、C反应蛋白（C-reactive protein，CRP）含量升高均为肥胖型中青年糖尿病患者颈内动脉斑块内有新生血管生成的独立危险因素（OR=1.047，1.388，2.319，2.094，1.951，P＜0.05或P＜0.01）。
结论 SMI对颈内动脉闭塞具有较高的诊断价值，与DSA检测结果具有较高的一致性，且有吸烟史、有冠心病史、有脑梗死病史及血清LDL-C、CRP含量升高均为肥胖型中青年糖尿病患者颈内动脉斑块内有新生血管生成的独立危险因素。


关键词: 超声检查, 颈动脉疾病, 危险因素

Abstract: Objective To explore the evaluation value of superb micro-vascular imaging(SMI) for internal carotid artery occlusion(ICAO) and to analyse the risk factors of plaque neovascularization. 
Methods  A total of 120 young and middle-aged obese patients with diabetes who had homogeneous iso-echo or hypoechoic plaques in the carotid artery detected in the Department of Ultrasound Medicine of our hospital were selected and detected by SMI and Digital subtraction angiography(DSA) for ICAO. They were divided into neovascularization group(n=98) and non-neovascularization group(n=22) according to the results of SMI detection. The clinical data of patients in two groups were collected for univariate analysis, and risk factors for plaque neovascularization were analyzed using multivariate unconditioned Logistic regression analysis. 
Results The probability of ICAO among 120 patients detected by SMI and DSA was 13.33% and 18.33% respectively, and the test results were in good consistency(Kappa=0.814, P=0.023). Smoking history, history of coronary heart disease(CHD), history of cerebral infarction as well as increased serum low-density lipoprotein cholesterol(LDL-C) and C-reactive protein(CRP) levels were the independent risk factors for plaque neovascularization in young and middle-aged obese patients with diabetes(OR=1.047, 1.388, 2.319, 2.094, 1.951, P＜0.05 or P＜0.01). 
Conclusion SMI has a high diagnostic value for ICAO, which in good consistency with DSA examination results. Smoking history, history of CHD, history of cerebral infarction and increased serum LDL-C and CRP levels are the independent risk factors for plaque neovascularization in young and middle-aged obese patients with diabetes.


Key words: ultrasonography, carotid artery diseases, risk factors

版权所有 © 《河北医科大学学报》编辑部
本系统由北京玛格泰克科技发展有限公司设计开发