河北医科大学学报 ›› 2024, Vol. 45 ›› Issue (11): 1317-1321.doi: 10.3969/j.issn.1007-3205.2024.11.013

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非球面人工晶状体成像质量的蒙特卡洛分析

  

  1. 河北医科大学第二医院眼科，河北 石家庄 050000

  • 出版日期:2024-11-25 发布日期:2024-11-26
  • 作者简介:田琨（1989-），女，河北石家庄人，河北医科大学第二医院主治医师，医学硕士，从事眼科疾病诊治研究。
  • 基金资助:
    河北省自然科学基金京津冀基础研究合作专项项目（H2023206907）

Monte Carlo analysis of imaging quality of aspherical intraocular lens

  1. Department of Ophthalmology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China

  • Online:2024-11-25 Published:2024-11-26

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摘要： 目的 模型眼中植入球面人工晶状体（intraocular lens，IOL），0 μm非球面IOL、-0.1 μm非球面IOL、-0.26 μm非球面IOL，四种不同球差的IOL，通过蒙特卡洛分析的方法比较每种IOL分别在瞳孔直径3 mm、4 mm和5 mm时较好10%和较差10%的调制传递函数（modulation transfer function,MTF）值，比较4种IOL成像质量及抗偏心性能的研究。
方法 实验研究中，分别在瞳孔直径3 mm、4 mm、5 mm条件下，在模型眼中插入4种不同球差的IOL。在计算机光学模拟系统中，通过蒙特卡洛分析的方法设计4种IOL随机0~0.5 mm偏心，分别进行1 000次随机模拟。比较四种IOL最好10%和最差10%成像质量的实验研究。
结果 随机偏心的情况下，在3 mm瞳孔直径条件下，最好10%时-0.1 μm非球面IOL与-0.26 μm非球面IOL、0 μm非球面IOL的MTF值均较高，且明显优于球面IOL，最差10%时-0.1 μm非球面IOL的MTF值较-0.26 μm非球面IOL和球面IOL高。在4 mm瞳孔直径条件下，最好10%时-0.1 μm非球面IOL与-0.26 μm非球面的MTF值较-0 μm非球面IOL和球面IOL高，最差10%时-0.1 μm的非球面IOL的MTF值较-0.26 μm非球面IOL和球面IOL高。在5 mm瞳孔直径条件下，最好10%时-0.1 μm非球面IOL的MTF值较0 μm非球面IOL和球面IOL高，最差10%时-0.1 μm非球面IOL的MTF较其他三种IOL高。
结论 -0.1 μm非球面IOL对偏心有较好的耐受性，成像质量的稳定性较高。


关键词: 白内障, 晶体, 人工, 蒙特卡洛分析

Abstract: Objective The model eyes were implanted with four kinds of intraocular lens (IOL) with different spherical aberration, including spherical IOL, 0 μm aspheric IOL, -0.1 μm aspheric IOL, -0.26 μm aspheric IOL.The 10% better and 10% worse Modulation transfer function (MTF) values of each IOL at 3 mm, 4 mm and 5 mm pupil diameters were compared using Monte Carlo analysis, and the imaging quality and anti-decentration performance were compared. 
Methods For experimental study, four kinds of IOL with different spherical aberration were inserted into the model eye under the condition of pupil diameter of 3 mm, 4 mm and 5 mm, respectively. In the computer optical simulation system, the Monte Carlo analysis method was used to design four kinds of IOL with random 0-0.5 mm decentration, and 1 000 random simulations were performed respectively. The experimental studies with the 10% better and 10% worse image quality of the four IOL were compared. 
Results In the case of random decentration, under the 3 mm pupil diameter, the MTF values of -0.1 μm aspherical IOL, -0.26 μm aspherical IOL and 0 μm aspherical IOL were higher than spherical IOL at the best 10%, and the MTF value of -0.1 μm aspherical IOL was higher than -0.26 μm aspherical IOL and spherical IOL at the worst 10%. Under the 4 mm pupil diameter, the MTF values of -0.1 μm aspherical IOL and -0.26 μm aspherical IOL 10% were higher than -0 μm aspherical IOL and spherical IOL at the best 10%, and the MTF values of -0.1 μm aspherical IOL were higher than those of -0.26 μm aspherical IOL and spherical IOL at the worst 10%. Under the 5 mm pupil diameter, the MTF value of -0.1 μm aspherical IOL was higher than 0 μm aspherical IOL and spherical IOL at the best 10%, and the MTF value of -0.1 μm aspherical IOL was higher than that of the other three IOL at the worst 10%. 
Conclusion -0.1 μm aspherical IOL has good tolerance to decentration and high stability of image quality. 


Key words: cataract, lenses, artificial, Monte Carlo analysis

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