河北医科大学学报

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3种不同术式治疗伴Ⅰ度退行性滑脱的腰椎管狭窄症效果观察

  

  1. 河北省石家庄市第一医院骨三科,河北 石家庄 050011
  • 出版日期:2016-07-25 发布日期:2016-08-11
  • 作者简介:李一鹏( 1980- ),男,河北威县人,河北省石家庄市 第一医院主治医师,医学硕士,从事骨科疾病诊治研究。
  • 基金资助:
    河北省医学科学研究重点课题( ZL20140288 )

The effect of three different surgical treatment on lumbar stenosis withⅠdegree degenerative spondylolisthesis

  1. Department of Orthopaedics Ⅲ, the First Hospital of Shijiazhuang City, Hebei Province, Shijiazhuang 050011, China
  • Online:2016-07-25 Published:2016-08-11

摘要: [摘要] 目的 观察单纯减压、椎间孔入路椎间融合术( transforaminallumbarinterbodyfusion , TLIF )、经后路
椎间融合术(
posteriorlumbarinterbodyfusion , PLIF )治疗伴 Ⅰ 度退行性滑脱的腰椎管狭窄症的效果。方法 选择
伴 Ⅰ 度退行性滑脱的腰椎管狭窄症患者 103 例,均为单侧症状严重者,分为 3 组:单纯减压组 38 例、 TLIF 组 31 例
和 PLIF 组 34 例。比较 3 组术中指标及术后 6 个月、 2 年随访时的滑脱程度、腰腿疼痛视觉模拟评分法( Visual
AnalogueScale , VAS )评分、日本骨科协会( JapaneseOrthopedicAssociation , JOA )评分,比较 TLIF 组及 PLIF 组术
后植骨融合情况,比较 3 组治疗效果。结果 TLIF 组和 PLIF 组手术时间、术中失血量及术后引流量明显多于单纯
减压组,而术后卧床时间明显少于单纯减压组。 PLIF 组手术时间、术中失血量及术后引流量显著多于 TLIF 组
( P <0.05 )。 3 组间疗效和并发症发生率差异无统计学意义( P >0.05 )。 TLIF 组及 PLIF 组腰疼痛 VAS 评分呈
逐渐下降趋势,单纯减压组腰疼痛 VAS 评分呈先下降后升高趋势, 3 组腿疼痛 VAS 评分均呈下降趋势, 3 组不同
时点间、组间·不同时点间交互作用差异有统计学意义( P <0.05 )。 TLIF 组及 PLIF 组术后 6 个月及 2 年时滑脱
程度逐渐降低,单纯减压组滑脱程度呈逐渐加重趋势,
3 组组间、不同时点间、组间·不同时点间交互作用差异均有
统计学意义( P <0.05 )。术后 6 个月复查时,
TLIF 组未融合 1 例, PLIF 组未融合 2 例;术后 2 年复查时, 2 组均融
合。结论 对于伴 Ⅰ 度退行性滑脱的腰椎管狭窄症患者,单纯开窗减压手术损伤小, TLIF 和 PLIF 的远期效果更
佳。 TLIF 手术失血量、住院时间、对神经和硬膜损伤等均少于
PLIF 。应用 TLIF 手术治疗伴 Ⅰ 度退行性滑脱的腰
椎管狭窄症更安全、有效。

关键词: 椎管狭窄, 脊椎滑脱, 脊柱融合术

Abstract: [
Abstract ] Objective Tocomparetheeffectsofsimpledecompression , transforaminal
lumbarinterbodyfusion ( TLIF ), posteriorlumbarinterbodyfusion ( PLIF ) onlumbarstenosis
withⅠdegreedegenerativespondylolisthesis.Methods Onehundredandthreecaseswithsevere
unilateral symptoms , suffering from lumbar stenosis with Ⅰ degree degenerative
spondylolisthesis weredivededintothreegroups : simpledecompression group ( 38cases ),
transforaminallumbarinterbodyfusion ( TLIF , 31cases ) andposteriorlumbarinterbodyfusion
(
PLIF , 34cases ) .Intraoperativeindex , thedegreeofspondylolisthesis , lumbocruralpainvisual
analoguescale ( VAS ), andJapaneseOrthopedicAssociation ( JOA ) scorewerecomparedinthe3
groupsat6 monthsand2yearsoffollow-up.postoperativebonegraftfusionsituation were comparedinTLIFandPLIFgroup.Theefficaciesoftreatmentofthe3groupswereanalyzed.
Results Theoperationtime , intraoperativebloodlossandoperationdrainageofTLIFgroupand
PLIFgroup weresignificantly higherthanthoseofsimpledecompression group , andthe
postoperativebedresttimewassignificantlylowerthanthatofsimpledecompressiongroup.The
operationtime , intraoperative bloodlossand postoperativedrainageofPLIF groups were
significantlyhigherthanthoseofTLIFgroup ( P <0.05 ) .Therewasnosignificantdifferencein
thecurativeeffectandcomplicationrateinthe3groups ( P >0.05 ) .lumbagoVASscorewas
graduallydecreasedinTLIFandPLIFgroup , butwasdecreasedfirstandthenincreasedsimple
decompressiongroup.VASscoreoflegpainin3groupsweredecreased.Thereweresignificant
differencesintheinteractionbetweenthetwogroupsatthesametime , thedifferencebetweenthe
twogroups ( P >0.05 ) .ProgressionofspondylolisthesisofTLIFandPLIFatpostoperative6
monthsand2 years weredecreased gradually , butsimpledecompression group showeda
graduallyincreasingtrend , andthedifferenceisstatisticallysignificantinthegroupsandtime
pointsandtheinteractionofthegroupsandtimepoints ( P <0.05 ) .At6monthsafteroperation ,
onepatientintheTLIFgroupwerenotfused , 2patientsinPLIFgroupwerenotfused.After2
yearsoffollow-up , allpatientsinthetwogroupswerefused.Conclusion ForIdegreeof
degenerativespondylolisthesisoflumbarspinalcanalstenosis , theinjuryofsimplefenestration
decompressionissmall.Thelong-termeffectofTLIFandPLIFisbetter.Theamountofblood
loss , lengthofstay , andtheinjuryofnerveanddurainPLIF weresuperiortoTLIF.TLIF
surgicalismoresafeandeffectivefortreatmentwithIdegreeofdegenerativespondylolisthesisof
lumbarspinalcanalstenosis.

Key words: spinalstenosis , spondylolysis , spinalfusion