河北医科大学学报

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我国大陆地区甲状腺结节患病率Meta分析

  

  1. 1.河北医科大学第二医院内分泌科,河北 石家庄 050000;2.河北医科大学第三医院脊柱外科,河北 石家庄 050051;3. 河北医科大学第二医院体检中心,河北 石家庄 050000;4. 河北医科大学第二医院感染科,河北 石家庄 050000
  • 出版日期:2017-02-25 发布日期:2017-03-10
  • 基金资助:
    河北省医学科学研究重点课题(20160136)

Prevalence of thyroid nodules in mainland China:a Metaanalysis

  1. 1.Department of Endocrinology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000,
    China; 2.Department of Spinal Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang
    050051, China; 3.Department of Physical Examination Center, the Second Hospital of Hebei
    Medical University, Shijiazhuang 050000, China; 4.Department of Infection, the Second
    Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2017-02-25 Published:2017-03-10
  • Supported by:
    霍立双(1988-),女,河北邢台人,河北医科大学第二医院医学硕士研究生,从事内分泌与代谢疾病诊治研究。

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗通过Meta分析了解我国大陆地区甲状腺结节的患病率。
〖HTH〗方法〖HTSS〗〖KG*2〗检索中国知网、中国科技期刊数据库及万方数据库中关于甲状腺结节患病率的相关文献。采用Stata 12.0软件进行数据合并估算患病率,并对性别、年龄、文化程度等因素进行亚组分析。
〖HTH〗结果〖HTSS〗〖KG*2〗共纳入68个研究,研究总样本量为560 877例,甲状腺结节患者190 228例。Meta分析结果显示,我国大陆地区甲状腺结节患病率为32%[95%CI 30%~34%],其中男性患病率为26%,女性患病率为39%。
〖HTH〗结论〖HTSS〗〖KG*2〗健康体检中甲状腺结节的总检出率偏高,且随年龄增长而增加,女性高于男性。文化程度越高,甲状腺结节的患病率越高,不同省份中河北、辽宁、北京地区甲状腺结节的患病率偏高。尿碘水平较低是甲状腺结节的危险因素,肥胖、糖代谢异常也与甲状腺结节的风险增加显著相关。

关键词: 甲状腺结节, 患病率, Meta分析

Abstract: [Abstract]  Objective〖HTSS〗〓To understand the prevalence of thyroid nodules in mainland China by using Metaanalysis.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Literature search was conducted to collect studies on the prevalence of thyroid nodules patients in China National Knowledge Internet, Chinese science&technology journal database and Wanfang database. Stata 12.0 software was used to estimate the prevalence of thyroid nodules,as well as on gender,age, degree of education and other factors to make subgroup analysis.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓A total of 68 studies ,including a total size of 560 877 and 190 228 patients of thyroid nodules, were eligible for inclusion in the review.The pooled analysis showed that prevalence of thyroid nodules was 32%[95%CI 30%-34%],the prevalence rates of thyroid nodules appeared 26% in male and 39% in female.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Incidence rate of thyroid nodules was high and increased with the age increased.More cases were found in females than in males. The higher of cultural degree,the higher the prevalence of thyroid nodules. The prevalence of thyroid nodule in Hebei, Liaoning and Beijing area is higher in different provinces.  Low iodine intake may increase the risk of thyroid nodule. An increased risk of thyroid nodule was respectively associated with obesity and abnormal glucose metabolism.

Key words: thyroid nodule, prevalence, Metaanalysis