河北医科大学学报

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病灶持续冲洗在脊柱结核并发脓肿手术治疗中的应用价值

  

  1. 河北省胸科医院骨科,河北 石家庄 050041
  • 出版日期:2017-04-25 发布日期:2017-04-25
  • 作者简介:刘丰胜(1962-),男,满族,河北承德人,河北省胸科医院主任医师,医学学士,从事骨科疾病诊治研究。
  • 基金资助:
    河北省医学科学研究重点课题(20150142)

  1. Department of Orthopedics, the Chest Hospital of Hebei Province, Shijiazhuang 050041,China
  • Online:2017-04-25 Published:2017-04-25

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨病灶持续冲洗在脊柱结核并发椎旁脓肿手术治疗中的效果及应用价值。
〖HTH〗方法〖HTSS〗〖KG*2〗选取脊柱结核并发椎旁脓肿患者97例,所有患者术前均常规应用抗结核药物治疗2~4周,手术均采用病灶清除植骨融合内固定术,将97例患者随机分为病灶持续冲洗组(冲洗组)51例和常规引流组(引流组)46例。冲洗组术后冲洗时间7~21 d,平均冲洗时间(16.0±4.8) d;常规引流组46例,术后常规引流2~10 d,平均(7.0±2.3) d,引流液<50 mL/24 h时拔除引流管。观察2组切口愈合、局部积液、早期体温变化、骨融合情况。
〖HTH〗结果〖HTSS〗〖KG*2〗术后1~7 d冲洗组体温呈降低趋势,引流组体温上下波动,冲洗组低于引流组,组间、不同时点间差异有统计学意义(P<005),而组间·不同时点交互作用差异无统计学意义(P>005)。术后21 d 2组红细胞沉降率均低于术前,但2组差异无统计学意义(P>005)。2组术后积液发生率差异有统计学意义(P<005),窦道发生率、二次手术率差异无统计学意义(P>005)。2组术后1年均达到骨性融合。
〖HTH〗结论〖HTSS〗〖KG*2〗脊柱结核行病灶清除植骨内固定后行持续病灶冲洗可减轻术后炎症反应,能够明显降低术后发热、积液、积脓以及病灶早期不愈的发生率,对骨病灶愈合和植骨融合无不良影响。对有适应证的患者进行此项治疗是治疗脊柱结核的有效方法之一。

关键词: 结核, 脊柱, 脓肿, 病灶冲洗

Abstract: [Abstract]  Objective〖HTSS〗〓To investigate the effect and value of application of continuous irrigation of lesions in the surgery of spinal tuberculosis combined with paraspinal abscess.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The clinical data of 97 patients with spinal tuberculosis complicated with paraspinal abscess were selected, all patients were routinely treated with antituberculosis drugs for 2 to 4 weeks before the operations of debridement and bone grafting with internal fixation. Ninetyseven patients were randomly divided into two groups, 51 cases in the continuous irrigating group and 46 cases in the conventional drainage group. The washing time of the continuous irrigating group was 7-21 days, average(16.0±4.8)  days. Fortysix cases in the conventional drainage group were given routine drainage for 2-10 days, average(7.0±2.3) days. The drainage tube were removed when the drainage fluid<50 mL/24 h. The incision healed, local effusion, early body temperature change and bone fusion of the two groups of patients were observed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓From day 1 to day 7 after operation, the body temperature of the continuous irrigating group decreased, while the conventional drainage group fluctuated up and down. the body temperature of the continuous irrigating group was lower than the other group. The body temperatures at different points between two groups were statistically significant(P<005). The difference of interaction of groups and time points were no statistically significant(P>005). In both groups, the erythrocyte sedimentation 21 days after operation were significantly decreased  compared with preoperation, but there were on statistically significant difference(P>005). The postoperative effusion rate between two groups were statistically significant(P<005).  The incidence of sinus and the rate of secondary surgery were no statistically significant(P>005). Two groups of patients achieved bony fusion 1 year after surgery.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓For the patients with spinal tuberculosis, continuous irrigation after the surgery of debridement and internal fixation can significantly reduce the postoperative effusion, empyema and the incidence of early unhealed lesions, reduce the postoperative fever incidence significantly, which is one of the effective methods of treating spinal tuberculosis.

Key words:  , tuberculosis, spinal; abscess; lesions irrigation