清创术联合420 nm强脉冲光治疗中重度痤疮凹陷性瘢痕和炎性红斑的效果观察

doi:10.3969/j.issn.10073205.2017.07.009

河北医科大学学报

清创术联合420 nm强脉冲光治疗中重度痤疮凹陷性瘢痕和炎性红斑的效果观察

河北医科大学第二医院整形外科，河北石家庄 05000

出版日期:2017-07-25 发布日期:2017-07-05
作者简介:韩兰芹（1965-），女，河北定州人，河北医科大学第二医院主管护师，从事临床护理学研究。

Study on the efficacy of debridement combined with 420 nm intense pulse light in the treatment of moderate to severe acne and depressed acne scarring and inflammatory erythema#br#

Department of Plastic Surgery, the Second Hospital of Hebei Medical University, Shijiahzuang 05000, China

Online:2017-07-25 Published:2017-07-05

摘要/Abstract

摘要： ［摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗观察清创术联合420 nm强脉冲光治疗中重度痤疮凹陷性瘢痕和炎性红斑的效果。
〖HTH〗方法〖HTSS〗〖KG*2〗将254例痤疮患者随机分为治疗组128例和对照组126例，治疗组采用清创术联合420 nm强脉冲光治疗，对照组采用420 nm强脉冲光治疗，每2周1次，共4次，2个月治疗结束后，进行疗效、凹陷性瘢痕和炎性红斑消退情况评价。
〖HTH〗结果〖HTSS〗〖KG*2〗2组临床疗效差异有统计学意义（P＜001）。凹陷性瘢痕清除评价，治疗组满意度92.2%，对照组满意度69.8%,差异有统计学意义（P＜001）。炎性红斑消退时间比较，治疗组短于对照组，差异有统计学意义（P＜001）。
〖HTH〗结论〖HTSS〗〖KG*2〗清创术联合420 nm强脉冲光治疗中重度痤疮效果显著，凹陷性瘢痕的发生率明显降低，可以促进炎性红斑消退。

关键词: 寻常痤疮, 清创术, 瘢痕

Abstract: 〗［Abstract］ Objective〖HTSS〗〓 To study the efficacy of debridement combined with 420 nm intense pulsed light in the treatment of the moderate to severe acne and the depressed scar and inflammatory erythema.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Two hundred and fiftyfour cases of acne patients were divided into two groups. One hundred and twentyeight cases as the treatment group were treated with acne debridement and 420 nm intense pulsed light, 126 cases as the control group were treated with 420 nm intense pulsed light. 1 times every 2 weeks, a total of 4 times. After 2 months in the end of treatment，the curative effect, occurrence of depressed scar and regression of inflammatory erythema were evaluated.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The differences in clinical efficacy were statistically significant（P＜001）. The satisfaction of depressed scar was 92.2% in treatment group and 69.8% in control group, there was a significant difference between the two groups(P＜001). As for the extinction time of inflammatory erythema, the treatment group was also significantly faster than the control group(P＜001).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Debridement combined with 420 nm intense pulsed light in treatment of moderate to severe acne is more effective than 420 nm intense pulsed light alone. The occurrence of epression scar was significantly reduced, while the inflammatory erythema was promoted.

Key words: acne vulgaris, debridement, cicatrix

韩兰芹，赵雪莲，张春莉，张〓洁，韩〓朋. 清创术联合420 nm强脉冲光治疗中重度痤疮凹陷性瘢痕和炎性红斑的效果观察[J]. 河北医科大学学报, doi: 10.3969/j.issn.10073205.2017.07.009.

HAN Lanqin, ZHAO Xuelian, ZHANG Chunli, ZHANG Jie, HAN Peng . Study on the efficacy of debridement combined with 420 nm intense pulse light in the treatment of moderate to severe acne and depressed acne scarring and inflammatory erythema#br#[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2017.07.009.

[1]	范龙坤, 刘春晖, 赵钰佳, 马超. 骨髓间充质干细胞来源外泌体通过TGF-β1/smad2/3信号通路抑制增生性瘢痕的机制研究 [J]. 河北医科大学学报, 2023, 44(8): 876-882,899.
[2]	侯芳娟, 韩宁. 子宫瘢痕妊娠子宫动脉栓塞术治疗侧支动脉形成的危险因素调查[J]. 河北医科大学学报, 2022, 43(1): 75-79.
[3]	张苏瑞, 刘维, 陈峰, 谭晓蕾, 王瑞超, 王录叶. 超脉冲CO2点阵激光联合重组牛碱性表皮生长因子凝胶治疗面部术后凹陷性瘢痕的效果及安全性[J]. 河北医科大学学报, 2021, 42(2): 201-204.
[4]	李萍, 庞义存, 梁军, 刘秀萍. 精准超声分型在剖宫产术后子宫瘢痕妊娠治疗中的应用研究[J]. 河北医科大学学报, 2021, 42(12): 1455-1459.
[5]	刘晓莉. 阿达帕林凝胶辅助超分子水杨酸、类人胶原蛋白敷料治疗轻中度痤疮患者的效果观察[J]. 河北医科大学学报, 2021, 42(10): 1189-1193,1209.
[6]	刘洪君, 孙雪美, 孙明强, 金春琳. 蒲公英甾醇通过TGF-β/Smad通路对小鼠痤疮模型炎症因子水平、胸腺组织形态的影响[J]. 河北医科大学学报, 2020, 41(7): 810-814.
[7]	刘鸿雁，蒋婷*，黄文炼，蒲晓姝. rhEGF联合皮肤软组织扩张器对面颈部瘢痕整形患者TLR4水平和Ⅰ/Ⅲ型胶原比值的影响[J]. 河北医科大学学报, 2020, 41(5): 566-569.
[8]	孙东霞1，郝亚宁2，李毅飞1，祁美玉1，王〓艳3,肖学茹1. 剖宫产术后瘢痕子宫妊娠至足月选择阴道试产成功孕妇与再次剖宫产孕妇临床资料分析[J]. 河北医科大学学报, 2019, 40(6): 729-732.
[9]	孙东霞1，郝亚宁2*，李毅飞1，祁美玉1，王〓艳3,肖学茹1. 剖宫产术后瘢痕子宫再次妊娠至足月二次剖宫产的临床研究[J]. 河北医科大学学报, 2019, 40(5): 597-599.
[10]	王成书，闫〓璐，黄向华*，贾〓雯. 妊娠子宫完全破裂22例临床结局及防治措施[J]. 河北医科大学学报, 2019, 40(2): 185-187,192.
[11]	严凤，李全香*，魏杏茹，付琳琳，胡美丽，陈伟静. 高强度聚焦超声治疗剖宫产瘢痕部位妊娠的效果分析#br#[J]. 河北医科大学学报, 2019, 40(12): 1413-1416.
[12]	聂〓婵1，王〓涛1，施尚鹏1，邓呈亮2，石修权1，3*. 烧伤对儿童伤残率和瘢痕率的影响分析#br#[J]. 河北医科大学学报, 2018, 38(1): 58-63.
[13]	胡玉芹;刘萍;梁伟国;黄淑华;郝辰珺;卢宇青. 子宫动脉栓塞术后清宫与腹腔镜下病灶切除术在子宫瘢痕妊娠治疗中的应用[J]. , 2015, 36(9): 1026-1026.
[14]	张志敏;杨玉秀;张海娟;张雪玲. 瘢痕子宫再次妊娠分娩方式的探讨[J]. , 2014, 35(9): 1067-1067.
[15]	李娟;任丽青;张翠娜;白永强. 护理干预对烧伤患者出院后抗瘢痕行为能力的影响[J]. , 2014, 35(7): 765-765.

清创术联合420 nm强脉冲光治疗中重度痤疮凹陷性瘢痕和炎性红斑的效果观察

Study on the efficacy of debridement combined with 420 nm intense pulse light in the treatment of moderate to severe acne and depressed acne scarring and inflammatory erythema#br#

HTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价