关键词: 直肠脱垂, 重建盆底, 吻合器痔上黏膜环切术

Abstract: ［Abstract］〓Objective〖HTSS〗〓To observe the therapeutic effect of pelvic floor reconstruction in combined with procedure for prolapse and hemorrhoids(PPH) in the treatment of Ⅱ and Ⅲ degree rectal prolapse and the effect on the inflammation and stress reaction.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 208 patients with rectal prolapse Ⅱ  and  Ⅲ  degrees were randomly divided into observation group(104 cases) and control group(104 cases). The patients in the observation group were given pelvic floor reconstruction in combined with PPH, while the patients in the control group were given rectal suspension in combined with anus reduces technique. The effectiveness in the two groups was compared. The postoperative inflammatory cytokines and stress reaction indicators in the two groups were compared in order to evaluate the effects.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The success rate of primary repair in the observation group was significantly higher than that of the control group, the incidence of postoperative complications was significantly lower than that of the control group, the difference was statistically significant(P＜005). The levels of cortisol（COR）, norepinephrine（NE）, prostaglandin E2（PGE2）, interleukin6（IL6）, interleukin10（IL10） and Creactive protein（CRP） in the two groups after treatment were significantly higher than those before treatment(P＜005). There were no significant differences in COR, NE, PGE2, IL6, IL10 and CRP between the two groups(P＞005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The pelvic floor reconstruction in combined with PPH can effectively treat Ⅱ, Ⅲ rectal prolapse in various degrees, reduce the occurrence rate and recurrence rate of postoperative complications. There was no obvious effect on postoperative inflammation and stress response, and has more obvious advantage when compared with Ⅱ, Ⅲ  rectal suspension in combined with anus reduces technique.

Key words: rectal prolapse, pelvic floor reconstruction, procedure for prolapse and hemorrhoids