河北医科大学学报

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不孕妇女心理应激状态对IVFET妊娠结局的影响#br#

  

  1. 河北医科大学第二医院生殖医学科,河北 石家庄 050000
  • 出版日期:2018-07-25 发布日期:2018-07-04
  • 作者简介:杨丛品(1984-),女,河北保定人,河北医科大学第二医院主管护师,医学学士,从事临床护理学研究。

Effect of psychological stress on IVFET pregnancy outcome in infertile women

  1. Department of Reproductive Medicine, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2018-07-25 Published:2018-07-04

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨初次接受体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVFET)妇女不同心理应激状况与妊娠结局之间的关系。
〖HTH〗方法〖HTSS〗〖KG*2〗将2016年1—12月首次在本院进行IVFET治疗的240例妇女根据抑郁自评量表(Selfrating Depression Scale,SDS)评分结果分为正常组和抑郁组,比较2组SDS、焦虑自评量表(Selfrating Anxiety Scale,SAS)和社会支持评分,以及获卵率、卵裂率、受精率、优质胚胎数、可利用胚胎率、妊娠率等指标。
〖HTH〗结果〖HTSS〗〖KG*2〗2组平均年龄差异无统计学意义。抑郁组不孕年限长于对照组、初中及以下学历所占比例大于正常组、高中或中专学历所占比例小于正常组,差异有统计学意义(P<005)。抑郁组SDS和SAS评分高于正常组,社会支持评分低于正常组,差异有统计学意义(P<005)。SDS评分和社会支持评分对妊娠结局有影响。
〖HTH〗结论〖HTSS〗〖KG*2〗不孕女性心理状况影响IVFET妊娠结局,关注其心理应激状态并进行相应护理和指导,可能对提高IVF妊娠成功率起到积极作用。

关键词: 体外受精, 胚胎移植, 抑郁

Abstract: [Abstract] Objective〖HTSS〗〓To investigate the relationship between the different psychological stress of first receiving in vitro fertilization and embryo transfer(IVFET) women and their pregnancy outcomes.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓According to the result of Selfrating Depression Scale(SDS)  score, 240 infertility patients who undergoing in vitro fertilization and embryo transfer in our hospital in January, 2016 to December,2016 were divided into normal group and depression group. The differences of  SDS, Selfrating Anxiety Scale(SAS), and social support score, the rate of eggs, fertilization rate, cleavage rate, high quality embryo number, embryo availability rate and pregnancy rate were compared between two groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The two groups were similar in terms of age. The duration of infertility and the proportion of middle school education was significantly higher in the depression group than in the control group, the proportion of high school or vocational level training was lower in the normal group(P<0.05). The mean scores of SDS and SAS in the depression group were significantly higher than those in the normal group, and the average scores in the social support group were lower than in the normal group(P<0.05). SDS scores and social support scores have an impact on pregnancy outcomes.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The psychological condition of infertile patients affects the outcome of IVFET pregnancy. Paying attention to the psychological stress state and carrying out the corresponding nursing and guidance, may play a positive role in improving the success rate of IVF pregnancy.

Key words: fertilization in vitro, embryo transfer, depression