河北医科大学学报

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甘肃陇南地区农村人群不同性别甲状腺结节患病状况调查

  

  1. 1.兰州大学第一医院内分泌科,甘肃 兰州 730000;2.甘肃省陇南市第一人民医院内分泌科,
    甘肃  陇南 746000;3.中国医科大学附属第一医院内分泌科,辽宁 沈阳 101100
  • 出版日期:2020-02-25 发布日期:2020-03-13
  • 作者简介:井高静(1988-),女,陕西渭南人,兰州大学第一医院主治医师,医学硕士研究生,从事内分泌代谢疾病诊治研究。
  • 基金资助:
    国家卫计委公益性行业科研专项(201402005)

Survey on the prevalence of thyroid nodules among different sexes in rural population in Longnan area of Gansu

  1. 1.Department of Endocrinology, the First Hospital of Lanzhou University, Gansu Prvince, Langzhou 
    730000,  China; 2.Department of Endocrinology, the First Hospital of Longnan City, Gansu Province,
    Longnan 730460,  China; 3.Department of Endocrinology, the First Affiliated Hospital of
    China Medical University, Liaoning Province, Shenyang  101100,  China
  • Online:2020-02-25 Published:2020-03-13

摘要: [摘要]
目的 调查甘肃陇南地区农村人群甲状腺结节患病率及不同情况下甲状腺结节检出率的差异。
方法 采用分层整群抽样方法对甘肃陇南地区进行横断面调查研究,分析不同性别、年龄、甲状腺功能组中甲状腺结节的检出率,并采用Logistic回归分析甲状腺结节的危险因素。
结果 甘肃陇南地区1 289例受检者中共检出甲状腺结节214例,总体患病率为16.60%(214/1 289),男性和女性患病率分别为13.04%(84/644)、20.16%(130/645),女性患病率明显高于男性(P<0.05);随着年龄增长,男性和女性甲状腺结节的患病率逐渐增加(P<0.05),且≥60岁组女性患病率明显高于男性(P<0.05)。在男性和女性中,甲状腺功能异常组中结节的检出率均明显高于甲状腺功能正常组(P<0.05)。Logistic回归分析结果显示,年龄≥60岁和吸烟为甲状腺结节的危险因素(P<0.05)。
结论 甘肃陇南地区女性甲状腺结节检出率高于男性,且随着年龄增长逐渐增加;甲状腺功能异常可能会影响甲状腺结节的发生。

关键词: 甲状腺结节, 患病率, Logistic模型

Abstract: 〗[Abstract] Objective To investigate the prevalence of thyroid nodules in rural population in Longnan area of Gansu.
Methods A stratified cluster sampling method was used to conduct a cross-sectional survey of the area. We analyzed the detection rate of thyroid nodules in different gender, age, and thyroid function groups, and used Logistic regression to analyze the risk factors of thyroid nodules.
Results A total of 214 thyroid nodules were detected in 1 289 subjects in Longnan, Gansu. The overall prevalence was 16.60%(214/1 289), and the prevalence of male and female were 13.04%(84/644) and 20.16%(130/645), and the prevalence of female significantly higher than male, the difference was statistically significant(P<0.05). With the increased of age, the prevalence of thyroid nodules in male and female increased gradually(P<0.05), and the prevalence of female was significantly higher in men≥60 years(P<0.05). In male and female, the detection rates of nodules in the abnormal thyroid function group were significantly higher than in the normal thyroid function group, and the differences were statistically significant(P<0.05). Logistic regression showed that age≥ 60 and smoking were risk factors for thyroid nodules.
Conclusion The detection rate of thyroid nodules in women in Longnan region of Gansu is higher than that of men, and it gradually increases with age. Abnormal thyroid function may affect the occurrence of thyroid nodules

Key words: thyroid no dule, prevalence; Logistic Models