2种尿液干化学分析仪检测血尿标本对策及评价

doi:10.3969/j.issn.1007-3205.2020.08.020

河北医科大学学报

2种尿液干化学分析仪检测血尿标本对策及评价

河北医科大学第二医院检验科，河北石家庄 050000

出版日期:2020-08-25 发布日期:2020-08-26
作者简介:杨洪乐（1976-），男，河北文安人，河北医科大学第二医院副主任检验师，医学硕士，从事临床检验研究。

The method and evaluation of hematuria detection in two kinds of urine dry chemistry analyzer

Department of Laboratory Medicine, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China

Online:2020-08-25 Published:2020-08-26

摘要/Abstract

摘要： 目的明确2种尿液干化学分析仪检测不同血红蛋白浓度血尿的规律，尝试探索相关处理对策。
方法制备15例不同血红蛋白浓度的模拟血尿样本，以科宝XL全自动尿液分析仪和贝克曼IRIS iQ200〖JP2〗全自动尿液分析仪分别进行离心前后的平行对照检测，对比分析11项检测指标。
结果当待检样本中血红蛋白浓度达到1 g/L〖JP〗时，科宝XL全自动尿液分析仪将会报告白细胞（white blood cell,WBC）假阳性结果，随着浓度不断加大，胆红素、亚硝酸盐、酮体、尿胆原、比重和维生素C依次产生假阳性结果；当待检样本中血红蛋白浓度达到5 g/L，贝克曼IRIS iQ200全自动尿液分析仪则报告胆红素假阳性结果，到达19 g/L时，KET产生假阳性结果。其他项目未见明显影响。
结论利用这2种尿液干化学分析仪进行不同血红蛋白浓度的血尿标本检测时，报告结果应结合各自的抗干扰能力特点。

关键词: 血尿, 血红蛋白, 干化学分析仪

Abstract: Objective To clarify the rules of two urine dry chemical analyzers in detecting hematuria with different hemoglobin concentrations, and to explore the relevant measures.
Methods Fifteen simulated hemoglobin samples with different hemoglobin concentrations were prepared. The parallel control tests were carried out in centrifugation or not with Kebao XL automatic urine analyzer and Beckman IRIS iQ200 automatic urine analyzer. 11 detection Results were compared and analyzed.
Results When the hemoglobin concentration in the sample arrive 1 g/L, the COMBI XL automatic urine analyzer will report the false positive Results of WBC. With the hemoglobin concentration increasing,bilirubin, nitrite, ketone body, urinary cholanogen, SG and vitamin C would be reported false positive Results in turn. When the hemoglobin concentration was 5 g/L, the Beckmann IRIS iQ200 automatic urine analyzer would report the false positive Results of BIL, and when it reached 19 g/L, KET false positive Results would appear. Other effects hadn't been found in these detections.
Conclusion When the hematuria samples in different hemoglobin concentrations were detected with the two urine dry chemical analyzers, their respective anti-interference characteristics should be taken consider.

Key words: hematuria, hemoglobin, dry chemical analyzer

杨洪乐, 杜欢欢, 杨丽妙, 李彦会, 宋建强, 汪冉. 2种尿液干化学分析仪检测血尿标本对策及评价[J]. 河北医科大学学报, doi: 10.3969/j.issn.1007-3205.2020.08.020.

YANG Hong-le, DU Huan-huan, YANG Li-miao, LI Yan-hui, SONG Jian-qiang, WANG Ran. The method and evaluation of hematuria detection in two kinds of urine dry chemistry analyzer[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.1007-3205.2020.08.020.

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2种尿液干化学分析仪检测血尿标本对策及评价

The method and evaluation of hematuria detection in two kinds of urine dry chemistry analyzer

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