关键词: 房颤, 杂交手术, 射频消融, 迷宫手术

Abstract: Objective  To evaluate the clinical value of hybrid surgery in the treatment of atrial fibrillation(AF) by comparing the therapeutic effects of three methods: hybrid surgery, surgery alone and radiofrequency ablation(RFA) alone.
Methods  Seventy-nine patients with valvular disease complicated by AF who were admitted to department of cardiovascular surgery, the first central hospital of Baoding were enrolled in this study. All patients underwent valve replacement. According to the treatment methods for AF, they were divided into hybrid surgery group, Cox-Maze procedure alone group(Maze group) and interventional ablation alone group. Hybrid surgery group and Maze group were treated with valve replacement and maze procedure under direct vision. Hybrid surgery group and interventional ablation alone group were treated in Department of Internal Medicine with interventional RFA at 3 months after operation. The patients were followed up for 1 year. ECG and echocardiography were reexamined at 3, 6, 9 and 15 months after valve replacement(at 1, 3, 6, and 12 months after intervention in hybrid surgery group and interventional ablation alone group). The recovery of the two groups was compared.
Results  The duration of medical intervention was shorter in hybrid surgery group than in interventional ablation alone group(P＜0.05). The cure rate of AF at 9 and 15 months was higher in hybrid surgery group than in Maze group and interventional ablation alone group, and the cure rate of AF at 9 and 15 months was higher in Maze group than in interventional ablation alone group(P＜0.05). All patients were reexamined by echocardiography and EF values were recorded. The differences in time points and time points between any two groups were statistically significant in the three groups(P＜0.05).
Conclusion  In the treatment of AF, hybrid surgery has a higher cure rate and a higher application value in clinical practice.

Key words: atrial fibrillation, hybrid surgery, radiofrequency ablation, maze surgery