关键词: 动脉硬化, 股动脉, 腘动脉

Abstract: Objective  To explore whether the use of vascutrak balloon to pretreat lesions will affect the efficacy of drug-coated balloon(DCB) in the treatment of femoral-popliteal atheroclesrotic occlusive disease.
Methods  The clinical data of 40 patients with femoral-popliteal atheroclesrotic occlusive disease treated in our center were retrospectively analyzed. Twenty cases underwent plain balloon angioplasty(PBA) combined with DCB(control group), while 20 cases received dual-wire balloon angioplasty and DCB(observation group). All patients were classified according to TASC grading standards, and the occurrence of perioperative adverse events was recorded. The ankle brachial index(ABI) was monitored before and at 3 months, 6 months, and 1 year after operation respectively. Rutherford classification was performed at 1-year follow-up.
Results  In both groups, the lesions were opened surgically in the true cavity and the surgery was performed. There was no significant difference in the length and stenosis of target vascular lesions between two groups(P＞0.05). The residual stenosis rate after pretreatment was less than 30%. There were 2 cases of distal embolization, one case in the observation group and one in the control group who was amputated ultimately. One patient in the control group had a restrictive dissection after balloon expansion, and received bail-out stenting. All 40 patients were followed up. The ABIs of the two groups were higher than those before operation, but gradually decreased at 3, 6, and 12 months after operation. The difference of interaction between groups, time points and time points between groups were statistically significant in two groups(P＜0.05).
Conclusion  For femoral-popliteal atheroclesrotic occlusive disease, vessel preparation with dual-wire balloon angioplasty and subsequent DCB, as compared with PBA combined with DCB, can decrease reintervention rate, and does not increase the incidence of complications, However, this conclusion still needs to be confirmed by large samples and long-term follow-up data.

Key words: arteriosclerosis, femoral artery, popliteal artery