Abstract: Objective To compare the diagnosis of MRI and 99 Tcm-MDP bone imaging in bone metastasis.Methods Fifteen patients of diagnosed bone metastatic tumor underwent MRI and 99 Tcm-MDP bone imaging,the positive rate was compared between the two methods.Results MRI showed positive examination in 15 cases,and a total 95 lesions.99 Tcm-MDP bone imaging showed positive examination in 1 3 cases and a total 6 1 lesions.The positive rate of MRI in detection lesions was higher than that of 99 Tcm-MDP bone imaging,the difference had statistical significance(χ2=23.684,P<0.01).Conclusion Post-contrasted T1 WI and DWI made MRI more sensitive than 99 Tcm-MDP bone imaging in examination of bone metastasis.MRI and bone scintigraphy are considered as the complementary diagnostic methods in the detection of bone metastasis.

Key words: bone neoplasms, neoplasm metastasis, magnetic resonance imaging, radionuclide imaging