Journal of Hebei Medical University

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Characteristics and related factors of coronary artery disease in premenopausal and postmenopausal women under 50 years of age

  

  1. 1.Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Yunnan
    Province, Kunming 650101,China; 2.Department of Cardiology, Zhongshan Hospital, Fudan
    University, Shanghai 200003, China; 3.Department of  Emergency, Dayao County
    People′s Hospital, Yunnan Province, Dayao 675400, China
  • Online:2018-10-25 Published:2018-09-27

Abstract: [Abstract] Objective〖HTSS〗〓To analyze the features of coronary artery disease and releated factors for postmenopausal and premenopausal women aged below 50  with coronary heart disease.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and fiftyfour female patients who were aged below 50 and diagnosed with coronary heart disease by coronary arteriography were divided into postmenopausal group(46 women) and premenopausal group(108 women). The features of coronary artery disease and releated factors for 2 groups of patients were compared and analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The age of the menopausal group was higher than that of the nonmenopausal group(P<001). Premenopausal group had less diabetes than the menopausal group, more smoking and more family history of coronary heart disease. Triacylglycerol in the premenopausal group was lower than that in the menopausal group. The premenopausal group was dominated by singlevessel disease, while the menopausal group was dominated by multivessel disease, and the difference was statistically significant(P<005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Coronary artery disease is not uncommon in premenopausal women with an increased incidence, but it is often underestimated in clinical practice and cannot be ignored in clinical work.

Key words: coronary disease, premenopause, menopause