Journal of Hebei Medical University ›› 2023, Vol. 44 ›› Issue (12): 1448-1452.doi: 10.3969/j.issn.1007-3205.2023.12.014
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Abstract: Objective Acute biliary pancreatitis (ABP) is caused by multiple factors. The aim of this study was to retrospectively analyze the characteristics of gallstone and biliary duct in patients with gallstones secondary to extrahepatic bile duct stones, so as to understand the risk factors and pathogenesis of ABP, providing the evidence to guide clinical diagnosis and treatment. Methods Retrospective analysis of medical records of patients with biliary stones admitted to the Department of Hepatobiliary Pancreatic and Splenic Surgery, the Affiliated Hospital of Medical University. Comprehensive analysis and grouping comparison were performed on clinical characteristics, laboratory indicators, and imaging characteristics of patients with and without ABP. Results A total of 28 patients with gallstones secondary to extrahepatic bile duct stones were found to have ABP, including 22 with mild acute pancreatitis (MAP), 3 with moderately severe acute pancreatitis (MSAP), and 3 with severe acute pancreatitis (SAP). One of 28 patients (3.6%) had a fatal outcome. Binary Logistics regression analysis revealed that diameter of cystic duct ≥5 mm, diameter of the smallest gallbladder stone <5 mm, mixed stone in the gallbladder, and pancreaticobiliary maljunction (PBM) remained highly correlated with ABP (OR value: 3.358, 4.414, 7.965 and 6.055, respectively). Conclusion The thickening of cystic duct, mixing of sediment and blocky small stones in the gallbladder, and pancreaticobiliary maljunction are strongly associated with the onset of ABP, which will provide evidence for the diagnosis, treatment and early warning of ABP in the future.
Key words: pancreatitis, cholecystolithiasis, diameter of cystic duct ,
DU Jun-wei, JIN Jun-hua. Analysis of risk factors of acute biliary pancreatitis [J]. Journal of Hebei Medical University, 2023, 44(12): 1448-1452.
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URL: https://xuebao.hebmu.edu.cn/EN/10.3969/j.issn.1007-3205.2023.12.014
https://xuebao.hebmu.edu.cn/EN/Y2023/V44/I12/1448