河北医科大学学报

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维持性血液透析患者再入院临床风险因素的分析

  

  1. 1.兰州大学第一临床医学院,甘肃 兰州 730000;2.兰州大学第一医院肾病科,甘肃 兰州 730000
  • 出版日期:2018-02-25 发布日期:2018-02-06
  • 作者简介:宋琼(1990-),女,陕西临潼人,兰州大学第一临床医学院医学硕士研究生,从事慢性肾脏病诊治研究。

Analysis of clinical risk factors for readmission in maintenance hemodialysis patients

  1. 1.The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China; 2.Department of
    Nephropathy, the First Hospital of Lanzhou University, Lanzhou 730000, China
  • Online:2018-02-25 Published:2018-02-06

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗分析慢性肾衰竭维持性血液透析患者6个月内再入院的临床风险因素,为临床预防提供依据。
〖HTH〗方法〖HTSS〗〖KG*2〗选取规律血液透析患者83例。根据6个月内是否发生2次及2次以上入院,将患者分为再入院组和未再入院组,对所有患者临床资料进行回顾性分析,探讨维持性血液透析患者再入院的相关临床风险因素。
〖HTH〗结果〖HTSS〗〖KG*2〗83例维持性透析患者中有42例6个月内再入院,再入院率为50.6%,再入院原因为心血管并发症14例(33.3%)、感染11例(26.2%),消化道症状8例(19.0%),血管通路不畅 5例(11.9%),呼吸衰竭2例(4.8%),脑卒中2例(4.8%)。再入院组患者中心静脉长期导管使用率明显高于未再入院组,城乡居民医保占比例高于未再入院组,入院时血红蛋白低于未再入院组,入院时血磷、氨基末端脑钠肽、超敏C反应蛋白高于未再入院组,出院时血红蛋白、白蛋白水平低于未再入院组,差异有统计学意义(P<005)。二元Logstic回归分析结果显示,血管通路、氨基末端脑钠肽、超敏C反应蛋白是维持性血液透析患者再入院的危险因素,出院时血红蛋白是维持性血液透析患者再入院的保护因素。
〖HTH〗结论〖HTSS〗〖KG*2〗维持性血液透析患者6个月内再入院率为50.6%,再入院率较高,主要原因包括心血管并发症、感染。再入院的危险因素包括血管通路、氨基末端脑钠肽、超敏C反应蛋白和出院时血红蛋白水平,影响因素较多,临床上应针对危险因素进行综合干预,以降低再入院率,提高患者的生活质量。

关键词: 肾透析, 病人再入院, 危险因素

Abstract: [Abstract]〓Objective〖HTSS〗〓To analyze the clinical risk factors of readmission within 6months among patients on maintenance hemodialysis for chronic renal failure so as to provide guidance for clinical prevention.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 83 hemodialysis patients were enrolled in the study. The patients were divided into readmission group and nonreadmission group according to whether there were two or more hospital admissions within 6months. The clinical data of all patients were retrospectively analyzed to identify readmission risk factors.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Among 83 patients, 42(50.6%) had a 6months hospital readmission. The readmission group had 14(33.3%) patients of cardiovascular complications, 11(26.2%) patients of infection, 8(19.0%) patients of digestive tract symptoms, 5(11.9%) patients of poor vascular access, 2(4.8%) patients of respiratory failure, 2(4.8%) patients of stroke. The utilization rate of central venous catheter in the readmission group was higher than that in the nonreadmission group. The proportion of medical insurance between urban and rural residents in the readmission group was higher than that in the nonreadmission group. The admission hemoglobin level was lower than that of the nonreadmission group, and the levels of admission serum phosphorus, Nterminal pro brain natriuretic peptide, hypersensitivity C reactive protein were higher than those of the non readmission group. The discharge hemoglobin and albumin levels were lower than those of the non readmission group, the difference was statistically significant(P<0.05). The logstic regression analysis indicated that the risk factors for the readmission included vascular access, Nterminal pro brain natriuretic peptide, hypersensitivity C reactive protein, and the protective factors included discharge hemoglobin.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The readmission rate was 50.6% in 6months in the maintenance hemodialysis patients, and the major causes of readmission were cardiovascular complications and infection. The risk factors for readmission include vascular access, Nterminal pro brain natriuretic peptide, hypersensitivity C reactive protein and discharge hemoglobin levels. The risk factors of readmission are influenced by many factors. Comprehensive intervention should be carried out according to the risk factors to reduce the incidence of readmission and improve the quality of life of patients.

Key words: renal dialysis, patient readmission, risk factors