河北医科大学学报

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癫痫儿童生活质量的影响因素及家庭干预的疗效分析

  

  1. 1.河北省保定市第一中心医院普儿科,河北 保定 071000;2.河北省秦皇岛市第一医院儿科,河北 秦皇岛 066000
  • 出版日期:2018-04-25 发布日期:2018-04-23
  • 作者简介:许蓓(1983-),女,河北保定人,河北省保定市第一中心医院主治医师,医学硕士,从事儿科疾病诊治研究。
  • 基金资助:
    秦皇岛市科学技术研究与发展计划(201502A230)

Factors affecting the quality of life in children with epilepsy and analysis of the effect of family intervention

  1. 1.Department of Pediatrics, Baoding First Central Hospital, Hebei Province, Baoding 071000, China;
    2.Department of Pediatrics, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China
  • Online:2018-04-25 Published:2018-04-23

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨癫痫儿童生活质量的影响因素并观察家庭干预的疗效。
〖HTH〗方法〖HTSS〗〖KG*2〗研究对象为138例癫痫儿童(研究组,联合家庭干预)和112例正常儿童(对照组)。分析不同性别、年龄、癫痫分型、疾病认知度、抗癫痫药物不良反应、发作频率、智力、抑郁、焦虑、文化程度、家庭人数、服药依从性、起病年龄等癫痫儿童的生活质量评分,比较治疗前后研究组家庭干预疗效和SF36评分与对照组的差异。分析影响癫痫发作的影响因素。
〖HTH〗结果〖HTSS〗〖KG*2〗全身发作较部分发作患儿生活质量评分低、疾病认知程度低者较疾病认知程度高者生活质量评分低、家庭收入较差者较家庭收入优越者生活质量评分低、对抗癫痫药有不良反应者生活质量评分低、发作频率1周3次以上者较1周3次以下者生活质量评分低、智力较低者较智力高者生活质量评分低、有抑郁和焦虑者较无抑郁和焦虑者生活质量评分低、文化程度较低者较文化程度较高者生活质量评分低、药物依从性低者较药物依从性高者生活质量评分低,差异均有统计学意义(P<005)。研究组经常规治疗+家庭干预后记忆力/注意力、学校表现、自我效能、健康观念和SF36总分均较治疗前明显提高,差异有统计学意义(P<005)。Logisitic回归分析显示,癫痫的全身性发作、对疾病认知度低、家庭收入差、智力较低、对抗癫痫药物有不良反应、发作频率高、有焦虑和抑郁、药物依从性差是影响癫痫患儿生活质量的重要因素。
〖HTH〗结论〖HTSS〗〖KG*2〗除了对癫痫患儿进行常规治疗外,还应进行家庭干预才能有效改善癫痫儿童的生活质量。

关键词: 癫痫, 生活质量, 影响因素, 儿童

Abstract: [Abstract] Objective〖HTSS〗〓To explore the influencing factors of life quality of epileptic children and observation of the effect of family intervention.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 138 children with epilepsy(study group, combined family intervention) and 112 healthy children(control group) were investigated. The quality of life on different gender, age, seizure type, cognitive level of disease, antiepileptic drug adverse reaction, seizure frequency, intelligence, depression, anxiety, educational level, family size, medication compliance, age of onset of epileptic children were analyzed. The effect of family intervention in the study group before and after treatment were compared, and the difference of SF36 score between the study group and the control group were compared.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The children with general seizures, low cognitive level of disease,poor family condition, adverse drug reactions, seizure frequency more than 3 times a week, lower intelligence, depression, anxiety, poor education level and medicine compliance have lower quality of life than the other group. The difference was statistically significant(P<005). After regular treatment and family intervention, memory/attention, school performance, selfefficacy, health concept and SF36 scores of the study group were significantly increased compared with those before family intervention, the difference was statistically significant(P<005). Logisitic regression analysis showed that epilepsy of generalized seizures, low cognitive level of disease, poor family income, low intelligence, adverse drug reactions, high attack frequency, anxiety, depression, poor education level and drug compliance were important factors for affecting the quality of life in children with epilepsy.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓In addition to regular treatment, we should also carry out family intervention to effectively improve the quality life of children with epilepsy.

Key words: epilepsy, quality of life, influence factors, child