河北医科大学学报

• 论著 • 上一篇    下一篇

2型糖尿病及非糖尿病患者的RDW与ACS冠状动脉病变严重程度的相关性分析

  

  1. 1.首都医科大学附属北京同仁医院急诊科,北京 100176;2.郑州大学第一附属医院心内科,河南 郑州 450052
  • 出版日期:2020-09-25 发布日期:2020-09-27
  • 作者简介:吴婷婷(1991-),女,北京人,首都医科大学附属北京同仁医院主治医师,医学硕士,从事心血管内科疾病诊治研究。
  • 基金资助:
    河南省医学科技攻关计划项目(2018020002)

The correlation between RDW of type 2 diabetes mellitus or non-diabeticpatients and severity of acute coronary syndrom

  1. 1.Department of Emergency, Beijing Tongren Hospital, Capital Medical University, Beijing
    100176, China; 2.Department of Cardiology, the First Affiliated Hospital of
    Zhengzhou University, Zhengzhou 450052, China
  • Online:2020-09-25 Published:2020-09-27

摘要: 目的  〖KG*2〗探讨急性冠状动脉综合征(acute coronary syndrome,ACS)冠状动脉血管严重程度与2型糖尿病(type 2 diabetes mellitus,2-DM)及非糖尿病患者红细胞分布宽度(red cell volume distribution width,RDW)水平的相关性。
〖HTH〗方法  〖KG*2〗选择ACS患者497,分为2-DM组(1组)213例、血糖正常组(2组)284例,分别行冠状动脉造影(coronary arteriography,CAG)根据SYNTAX评分将1组及2组分别为低分组(A组)、中分组(B组)、高分组(C组),测定各组的RDW,进行比较及相关性分析;测定1组内A、B、C 3组间的糖化血红蛋白水平,进行组内比较及相关性分析。
〖HTH〗结果  〖KG*2〗1组中A1、B1、C1与2组中A2、B2、C2 RDW水平进行性升高,差异有统计学意义(P<0.05),且RDW水平与SYNTAX评分呈正相关(r=0.675,P<0.01)。所有入选497例患者的RDW水平与SYNTAX评分呈正相关(r=0.686,P=0.041)。1组与2组RDW水平与SYNTAX评分相关系数差异无统计学意义(Z=-1.960,P=0.373)。
〖HTH〗结论  〖KG*2〗RDW不受血糖水平影响,不论是2-DM患者还是血糖正常的患者,均可以作为ACS冠状动脉血管严重程度的评价指标。

关键词: 急性冠状动脉综合征, 糖尿病, 2型, 红细胞分布宽度

Abstract: Objective  To investigate the correlation between the severity of acute coronary syndrome(ACS) and red blood cell distribution width(RDW) of type 2 diabetes mellitus(DM) and non-diabetic patients.
  Methods  The 497 ACS patients were selected and divided into the 2-DM group(group 1) and the non-diabetic group(group 2), performed coronary angiography(CAG) separately. According to SYNTAX score, group 1 and group 2 were divided into three groups: low group, middle group and high group(group 1:A1, B1, C1; group 2:A2, B2, C2), measuring the RDW width of each group, and conducting comparison and correlation analysis. Glycated hemoglobin(GHb) levels between groups A1, B1 and C1 were measured, and intra-group comparison and correlation analysis were performed.
  Results  The RDW level of A1, B1, C1 in group 1 and A2, B2 and C2 in group 2 was progressively increased with statistically significant difference(P<0.05), and the RDW level was positively correlated with SYNTAX score(r=0.675, P<0.01). The RDW level of all 497 patients was positively correlated with SYNTAX score(r=0.686, P=0.041). There was no statistically significant difference in the correlation coefficient between RDW level and SYNTAX score(Z=-1.960, P=0.373)between groups 1 and 2.
  Conclusion  The width of the red blood cells was not affected by the blood glucose level. Whatever type 2 diabetes mellitus and non-diabetic patients, RDW can be used as the evaluation index of the severity of ACS coronary blood vessels.

Key words: acute coronary syndrome, diabetes mellitus, type 2, red blood cell distribution width