Objective  To explore the value of transvaginal color Doppler ultrasound, colposcopy and their combination in the diagnosis of cervical cancer, and to provide assistance for clinical diagnosis. 
Methods  Clinical data of 62 patients with early cervical cancer and 28 patients with non-cervical cancer(19 cases of precancerous lesions and 9 cases of normal cervix) diagnosed by pathology were retrospectively analyzed. All patients were examined by transvaginal color Doppler ultrasound and colposcopy. The results of pathological examination were taken as the gold standard to compare the diagnostic value of transvaginal color Doppler ultrasound, colposcopy and their combination in cervical cancer. 
Results  A total of 61 cases of cervical cancer and 29 cases of non-cervical cancer were detected by color Doppler ultrasound, and Kappa coefficient was 0.769 compared with pathological results; 55 cases of cervical cancer and 35 cases of non-cervical cancer were detected by colposcopy,and Kappa coefficient was 0.588 compared with pathological results. Sixty cases of cervical cancer and 30 cases of non cervical cancer were detected by combination detection of color Doppler ultrasound and colposcopy and Kappa coefficient was 0.949 compared with pathological results.The sensitivity, specificity and coincidence rate of color Doppler ultrasound in the diagnosis of cervical cancer were 91.94%, 85.71% and 90.00%, respectively; the sensitivity, specificity and coincidence rate of colposcopy in the diagnosis of cervical cancer were 80.65%, 82.14% and 81.11%, respectively; the sensitivity, specificity and coincidence rate of colposcopy combined with colposcopy in the diagnosis of cervical cancer were 96.77%, 100.0% and 97.78%, respectively. PSV of cervical cancer patients was significantly lower than that of patients with precancerous lesions and normal cervix, RI was significantly higher than that of precancerous lesions and normal cervix, and the difference was statistically significant(P＜0.05). The AUC of PSV in diagnosis of cervical cancer was 0.908, and sensitivity and specificity were 90.3% and 85.7%respectively.The AUC of RI in diagnosis of cervical cancer was 0.819, with sensitivity and specificity of 77.4% and 67.9% respectively. 
Conclusion  Transvaginal color Doppler ultrasound and colposcopy have certain value in the diagnosis of cervical cancer, but the value of combination of the two in the diagnosis is higher. The combination diagnosis can effectively distinguish cervical cancer and precancerous lesions. In the meantime, transvaginal color Doppler ultrasound can also reveal blood flow of lesions, which can provide assistance for surgical treatment.