河北医科大学学报 ›› 2021, Vol. 42 ›› Issue (8): 944-949.doi: 10.3969/j.issn.1007-3205.2021.08.017

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石家庄市大学生对HPV认知状况及疫苗接种意愿调查

  

  1. 1.河北医科大学公共卫生学院2017级，河北 石家庄 050017；2河北医科大学流行病学与卫生统计学教研室，河北省环境与人类健康重点实验室，河北 石家庄 050017
  • 出版日期:2021-08-25 发布日期:2021-08-30
  • 作者简介:李欣怡（1999-），女，山东德州人，河北医科大学公共卫生学院2017级学生，从事流行病与医学统计学学习。
  • 基金资助:
    国家自然科学基金（81601876）；河北省自然科学基金（H2019206528）；河北省高等学校科学技术研究（BJ2019019，QN2015006）；大学生创新性实验计划（USIP2019238）

Investigation into cognition of HPV and vaccination willingness among college students in Shijiazhuang city

  1. 1.Grode 2017, School of Public Health, Hebei Medical University, Hebei Province, Shijiazhuang 
    050017, China; 2.Department of Epidemiology and Health Statistics, Hebei Medical University, 
    Hebei Province Key Laboratory for Environment and Human Health, 
    Hebei Province, Shijiazhuang 050017, China
  • Online:2021-08-25 Published:2021-08-30

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摘要： 目的  采用不同模型对不同知识得分情况进行分析，研究石家庄市大学生对人乳头瘤病毒（human papilloma virus，HPV）疫苗的接种意愿及其影响因素，为向石家庄市大学生HPV疫苗的推广提供理论基础和依据。
方法  采取随机抽样的方法，对石家庄市11所大学的大学生开展有关人口学、HPV及宫颈癌认知、性行为、HPV疫苗的认知和接种意愿的问卷调查，共收回1 622份有效问卷。采用卡方检验比较不同接种意愿的大学生在基本信息、性行为和感染自觉性上的差异，采用秩和检验比较不同接种意愿的大学生对HPV相关知识了解程度的差异，采用Logistic回归模型分析影响接种的因素。
结果  45.62%（740/1 622）的大学生表示愿意接种HPV疫苗，而54.38%（882/1 622）表示不愿意接种HPV疫苗。愿意接种组和不愿意接种组的学生的HPV相关问题总得分分别为6.000（8.000）和1.000（7.250），差异有统计学意义（P＜0.001），将总得分划分为HPV及宫颈癌相关知识得分和HPV疫苗相关知识得分2个维度及多个小维度后差异仍有统计学意义（P＜0.001)；Logistic回归分析的结果显示，HPV相关知识得分均与接种意愿有统计学关联（P＜0.001），分数越高，接种意愿也会随之增高；模型1、2、3在均衡生活费、性别、籍贯等因素后，OR值下降，模型4 加入性行为和感染风险自觉性后，相较于模型3 ，OR值上升。
结论  石家庄市大学生HPV疫苗接种的接受率低于全国水平，HPV疫苗接种率与相关知识有关，提高大学生HPV相关知识水平，会增加其对疫苗的接受率，故相关部门需加强宣传力度，增强大学生自我保护意识。


关键词: 乳头状瘤病毒疫苗, 影响因素分析, 大学生

Abstract: Objective  To study the vaccination willingness and influencing factors of human papillomavirus(HPV) for college students in Shijiazhuang City by using different models to analyze different knowledge scores, and to provide the theoretical basis for the promotion of HPV vaccine for college students in Shijiazhuang City. 
Methods  Using a random sampling method, a questionnaire on demography, HPV and cervical cancer cognition, sexual behavior, HPV vaccine cognition and vaccination intention was conducted universities in Shijiazhuang City, and a total of 1622 valid questionnaires were retrieved. The Chi-square test was used to analyze the differences in basic information, sexual behavior and infection consciousness of college students with different vaccination intentions. The Mann-Whitney U test was employed to observe the effect of HPV-related knowledge on vaccination intention in those students, and the Logistic regression model was used to analyze the factors affecting vaccination. 
Results  45.62%(740/1622) of college students expressed their willingness to receive HPV vaccine, while 54.38%(882/1622) expressed their unwillingness. The total scores for HPV-related issues were 6.000（2.000，10.000） and 1.000（-2.000，5.250） for students in the willingness and unwillingness groups respectively, with statistically significant differences(P＜0.001), The total score was divided into HPV score and cervical cancer-related knowledge score as well as HPV vaccine-related knowledge score, and the difference was still statistically significant（P＜0.001). The results of Logistic regression analysis showed that HPV-related knowledge score was statistically associated with vaccination willingness(P＜0.001); the higher the score, the higher the intention to vaccinate. After adjusting living expenses, gender, origin and other factors, OR value was decreased in models 1, 2, and 3; after taking sexual behavior and infection risk consciousness into consideration, OR value was increased in model 4, as compared with model 3. 
Conclusion  The acceptance rate of HPV vaccination for college students in Shijiazhuang City is lower than that at the national level. Therefore, improving HPV-related knowledge of college students will increase their acceptance rate of vaccines, and the relevant departments still need to strengthen publicity and efforts to enhance the awareness of self-protection of college students. 


Key words: papillomavirus vaccines, influencing factor analysis, college students

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